Duke Institute for Brain Sciences

My research explores the intersection between motivation, emotion, and memory. A fundamental brain function is to generate predictive models of the world. The fidelity of those neural models and their ability to support adaptive behavior is critically dependent on whether and how experience is recorded - and whether neural records remain viable. I am interested in understanding how internal states like excitement, desire, and craving shape long-term memory, giving some experiences more power than others to affect future behavior. To understand these interactions, we study the brain systems that release modulatory neurotransmitters: environmental stimuli that turn them on, their effects on plasticity in other brain regions, and ultimately our ability to control them. Research in my laboratory uses primarily functional neuroimaging but draws broadly from neuroscience. By understanding the neurobiology of powerful memories, we hope to understand how to enhance cognitive and behavioral change.

Psychiatry Residency, University of California, San Francisco

M.D., Yale University

Ph.D., Yale University

B.A., Emory University

Adcock, R.A., Thangavel, A., Whitfield-Gabrieli, S., Knutson, B., and Gabrieli, J.D.E. Reward-Motivated Learning: Mesolimbic Activation Precedes Memory Formation. Neuron. 50(3):507-17, 2006.

Knutson, B., Adcock, R.A. Remembrance of Rewards Past. Neuron. 45(3):331-2, 2005.