Duke Institute for Brain Sciences

Our lab focuses on the molecular mechanisms that control cell growth and differentiation in the cerebellum, and how these mechanisms are dysregulated in the cerebellar tumor medulloblastoma.

Postdoctoral Fellow, Stanford University, Neural Development, 1997-2001

Postdoctoral Fellow, Wistar Institute, Molecular Oncology, 1995-1996

Ph.D., University of Pennsylvania, Immunology, 1995

A.B., Harvard College, Psychology & Biology, 1986

Read TA, Fogarty MP, Markant SL, McLendon RE, Wei Z, Ellison DW, Febbo PG and Wechsler-Reya RJ (2009) Identification of CD15 as a Marker for Tumor-Propagating Cells in a Mouse Model of Medulloblastoma. Cancer Cell 15(2):135-147.

Kessler JD, Hasegawa H, Brun, SN, Emmenegger BA, Yang, ZJ, Dutton JW, Wang F and Wechsler-Reya RJ (2009) N-myc Alters the Fate of Pre-Neoplastic Cells in a Mouse Model of Medulloblastoma. Genes & Development. 23(2):157-170.

Yang ZJ, Ellis T, Markant SL, Read, TA, Kessler JD, Bourboulas M, Schüller U, Machold R, Fishell G, Rowitch, DH, Wainwright BJ and Wechsler-Reya RJ (2008) Medulloblastoma can be Initiated by Deletion of Patched in Lineage-Restricted Progenitors or Stem Cells. Cancer Cell. 14:135-45.