Molecular Mechanisms of Neural Circuit Assembly
Duke Neurobiology welcomes neuroscientist Liqun Luo, PhD, Ann and Bill Swindells Professor of Humanities and Sciences at Stanford University. Contact firstname.lastname@example.org for connection details. Abstract: The human brain contains ~1011 neurons, making >1014 synaptic connections that enable us to sense, think, remember, and act. How is this vast number of neurons organized into circuits to process information? How are these circuits correctly assembled during development? We use model neural circuits in the less numerically complex brains of the fruit fly (~105 neurons) and mouse (~108 neurons) to address these questions. In this talk, I will discuss our recent work on the assembly of the fly olfactory circuit and mouse hippocampal circuit, using molecular-genetic, transcriptomic, and proteomic approaches.