Alexey Gennadyevich Mukhin

Alexey Gennadyevich Mukhin

Professor of Psychiatry and Behavioral Sciences

External Address: 
Hock Plaza 2424 Erwin Rd. Suite 201, Box 2701 Medctr., Durham, NC 27710
Phone: 
919.668.5092

Overview

Education & Training

  • M.D., Second Moscow State Institute of Medicine (Russia) 1973

Selected Grants

E-cigarettes: deposition, absorption and brain accumulation of nicotine awarded by National Institutes of Health (Principal Investigator). 2017 to 2022

E-cigarettes: deposition, absorption and brain accumulation of nicotine awarded by National Institutes of Health (Principal Investigator). 2017 to 2022

Neural Circuitry Involved in Pulmonary Nicotine Sensation during Smoking awarded by (Principal Investigator). 2019 to 2021

The Role of Nicotine and Non-Nicotine Alkaloids in E-Cigarette Use and Dependence awarded by National Institutes of Health (Investigator). 2015 to 2020

Alpha 5 Nicotinic Receptor Subunit Gene Polymorphisms and Smoking Addiction awarded by National Institutes of Health (Principal Investigator). 2013 to 2019

Novel Approach to Quantify Nicotinic Receptor Upregulation in Smokers awarded by National Institutes of Health (Principal Investigator). 2014 to 2017

P50 Supplement awarded by National Institutes of Health (Research Scientist). 2010 to 2015

Effects of Cigarette Mentholation on Brain Nicotine Accumulation During Smoking awarded by National Institutes of Health (Co Investigator). 2011 to 2013

Improving the efficacy of anti-nicotine immunotherapy awarded by National Institutes of Health (Principal Investigator). 2009 to 2012

Zuo, Yantao, et al. “A programmable smoke delivery device for PET imaging with cigarettes containing 11C-nicotine..” J Neurosci Methods, vol. 283, May 2017, pp. 55–61. Pubmed, doi:10.1016/j.jneumeth.2017.03.016. Full Text

Le Foll, Bernard, et al. “Impact of short access nicotine self-administration on expression of α4β2* nicotinic acetylcholine receptors in non-human primates..” Psychopharmacology (Berl), vol. 233, no. 10, May 2016, pp. 1829–35. Pubmed, doi:10.1007/s00213-016-4250-9. Full Text

Zuo, Yantao, et al. “Sex-specific effects of cigarette mentholation on brain nicotine accumulation and smoking behavior..” Neuropsychopharmacology, vol. 40, no. 4, Mar. 2015, pp. 884–92. Pubmed, doi:10.1038/npp.2014.263. Full Text

Brody, Arthur L., et al. “Brain nicotinic acetylcholine receptor availability and response to smoking cessation treatment: a randomized trial..” Jama Psychiatry, vol. 71, no. 7, July 2014, pp. 797–805. Pubmed, doi:10.1001/jamapsychiatry.2014.138. Full Text

Brody, Arthur L., et al. “Treatment for tobacco dependence: effect on brain nicotinic acetylcholine receptor density..” Neuropsychopharmacology, vol. 38, no. 8, July 2013, pp. 1548–56. Pubmed, doi:10.1038/npp.2013.53. Full Text

Brody, Arthur L., et al. “Up-regulation of nicotinic acetylcholine receptors in menthol cigarette smokers..” Int J Neuropsychopharmacol, vol. 16, no. 5, June 2013, pp. 957–66. Pubmed, doi:10.1017/S1461145712001022. Full Text

Brody, Arthur L., et al. “Effect of secondhand smoke on occupancy of nicotinic acetylcholine receptors in brain..” Arch Gen Psychiatry, vol. 68, no. 9, Sept. 2011, pp. 953–60. Pubmed, doi:10.1001/archgenpsychiatry.2011.51. Full Text

Rose, Jed E., et al. “Kinetics of brain nicotine accumulation in dependent and nondependent smokers assessed with PET and cigarettes containing 11C-nicotine..” Proc Natl Acad Sci U S A, vol. 107, no. 11, Mar. 2010, pp. 5190–95. Pubmed, doi:10.1073/pnas.0909184107. Full Text

Le Foll, Bernard, et al. “Baseline expression of alpha4beta2* nicotinic acetylcholine receptors predicts motivation to self-administer nicotine..” Biol Psychiatry, vol. 65, no. 8, Apr. 2009, pp. 714–16. Pubmed, doi:10.1016/j.biopsych.2008.09.036. Full Text

Brody, Arthur L., et al. “Brain nicotinic acetylcholine receptor occupancy: effect of smoking a denicotinized cigarette..” Int J Neuropsychopharmacol, vol. 12, no. 3, Apr. 2009, pp. 305–16. Pubmed, doi:10.1017/S146114570800922X. Full Text

Pages