Alexey Gennadyevich Mukhin

Alexey Gennadyevich Mukhin

Professor in Psychiatry and Behavioral Sciences

External Address: 
Hock Plaza 2424 Erwin Rd. Suite 201, Box 2701 Medctr., Durham, NC 27710


Education & Training

  • M.D., Second Moscow State Institute of Medicine (Russia) 1973

Brody, Arthur L., et al. “Brain nicotinic acetylcholine receptor occupancy: effect of smoking a denicotinized cigarette.Int J Neuropsychopharmacol, vol. 12, no. 3, Apr. 2009, pp. 305–16. Pubmed, doi:10.1017/S146114570800922X. Full Text

Justinova, Zuzana, et al. “Fatty acid amide hydrolase inhibition heightens anandamide signaling without producing reinforcing effects in primates.Biol Psychiatry, vol. 64, no. 11, Dec. 2008, pp. 930–37. Pubmed, doi:10.1016/j.biopsych.2008.08.008. Full Text

Mukhin, Alexey G., et al. “Greater nicotinic acetylcholine receptor density in smokers than in nonsmokers: a PET study with 2-18F-FA-85380.J Nucl Med, vol. 49, no. 10, Oct. 2008, pp. 1628–35. Pubmed, doi:10.2967/jnumed.108.050716. Full Text

Kimes, Alane S., et al. “Quantification of nicotinic acetylcholine receptors in the human brain with PET: bolus plus infusion administration of 2-[18F]F-A85380.Neuroimage, vol. 39, no. 2, Jan. 2008, pp. 717–27. Pubmed, doi:10.1016/j.neuroimage.2007.09.015. Full Text

Chefer, Svetlana I., et al. “NIDA522131, a new radioligand for imaging extrathalamic nicotinic acetylcholine receptors: in vitro and in vivo evaluation.J Neurochem, vol. 104, no. 2, Jan. 2008, pp. 306–15. Pubmed, doi:10.1111/j.1471-4159.2007.05009.x. Full Text

Chefer, Svetlana I., et al. “Estimation of D2-like receptor occupancy by dopamine in the putamen of hemiparkinsonian Monkeys.Neuropsychopharmacology, vol. 33, no. 2, Jan. 2008, pp. 270–78. Pubmed, doi:10.1038/sj.npp.1301404. Full Text

Le Foll, Bernard, et al. “Validation of an extracerebral reference region approach for the quantification of brain nicotinic acetylcholine receptors in squirrel monkeys with PET and 2-18F-fluoro-A-85380.J Nucl Med, vol. 48, no. 9, Sept. 2007, pp. 1492–500. Pubmed, doi:10.2967/jnumed.107.039776. Full Text

Sorger, Dietlind, et al. “Measurement of the alpha4beta2* nicotinic acetylcholine receptor ligand 2-[(18)F]Fluoro-A-85380 and its metabolites in human blood during PET investigation: a methodological study.Nucl Med Biol, vol. 34, no. 3, Apr. 2007, pp. 331–42. Pubmed, doi:10.1016/j.nucmedbio.2006.12.008. Full Text

Vaupel, D. Bruce, et al. “Quantification of alpha4beta2* nicotinic receptors in the rat brain with microPET and 2-[18F]F-A-85380.Neuroimage, vol. 34, no. 4, Feb. 2007, pp. 1352–62. Pubmed, doi:10.1016/j.neuroimage.2006.10.036. Full Text

Shumway, Dean A., et al. “A simplified method for the measurement of nonmetabolized 2-[18F]F-A-85380 in blood plasma using solid-phase extraction.Nucl Med Biol, vol. 34, no. 2, Feb. 2007, pp. 221–28. Pubmed, doi:10.1016/j.nucmedbio.2006.12.001. Full Text