Allison Elizabeth Ashley-Koch
Professor in Medicine
Overview
Selected Grants
Genetic and Genomics Training Grant awarded by National Institutes of Health (Mentor). 2020 to 2025
NINDS Research Education Programs for Residents and Fellows in Neurosurgery awarded by National Institutes of Health (Mentor). 2009 to 2025
Identifying novel clinical, genetic and proteomic risk factors for sickle cell nephropathy. awarded by National Institutes of Health (Principal Investigator). 2021 to 2023
Trauma and Genomics Modulate Brain Structure across Common Psychiatric Disorders awarded by National Institutes of Health (Co Investigator). 2017 to 2022
RPE Exosomes in Age-related Macular Degeneration awarded by National Institutes of Health (Collaborator). 2021 to 2022
Modeling Sickle Cell Disease phenotypes through supervised learning of patient multi-omic data awarded by National Heart, Lung, and Blood Institute (Principal Investigator). 2020 to 2021
Bioinformatics and Computational Biology Training Program awarded by National Institutes of Health (Mentor). 2005 to 2021
Eyes of Africa: The Genetics of Blindness awarded by University of Ibadan (Investigator). 2017 to 2021
Transfusion Medicine and Hematology awarded by National Institutes of Health (Preceptor). 1975 to 2021
Sharing Comprehensive 'Omics in Sickle Cell Disease Through the NHLBI TOPMed Network awarded by Doris Duke Charitable Foundation, Inc. (Co Investigator). 2019 to 2020
Pages
Markunas, C. A., et al. “Genetics of the chiari I and II malformations.” The Chiari Malformations, 2020, pp. 289–97. Scopus, doi:10.1007/978-3-030-44862-2_23. Full Text
Markunas, C. A., et al. “Genetics of the Chiari i and II malformations.” The Chiari Malformations, vol. 9781461463696, 2013, pp. 93–101. Scopus, doi:10.1007/978-1-4614-6369-6_7. Full Text
Barrera, Julio, et al. “Sex dependent glial-specific changes in the chromatin accessibility landscape in late-onset Alzheimer's disease brains.” Mol Neurodegener, vol. 16, no. 1, Aug. 2021, p. 58. Pubmed, doi:10.1186/s13024-021-00481-0. Full Text
Liang, Dan, et al. “Cell-type-specific effects of genetic variation on chromatin accessibility during human neuronal differentiation.” Nature Neuroscience, vol. 24, no. 7, July 2021, pp. 941–53. Epmc, doi:10.1038/s41593-021-00858-w. Full Text
Hu, Benxia, et al. “Neuronal and glial 3D chromatin architecture informs the cellular etiology of brain disorders.” Nat Commun, vol. 12, no. 1, June 2021, p. 3968. Pubmed, doi:10.1038/s41467-021-24243-0. Full Text
Keramati, Ali R., et al. “Genome sequencing unveils a regulatory landscape of platelet reactivity.” Nat Commun, vol. 12, no. 1, June 2021, p. 3626. Pubmed, doi:10.1038/s41467-021-23470-9. Full Text
Sofer, Tamar, et al. “Variant-specific inflation factors for assessing population stratification at the phenotypic variance level.” Nat Commun, vol. 12, no. 1, June 2021, p. 3506. Pubmed, doi:10.1038/s41467-021-23655-2. Full Text
Ataga, Kenneth I., et al. “Rapid decline in estimated glomerular filtration rate in sickle cell anemia: results of a multicenter pooled analysis.” Haematologica, vol. 106, no. 6, June 2021, pp. 1749–53. Pubmed, doi:10.3324/haematol.2020.267419. Full Text
Wegermann, Kara, et al. “Sex and Menopause Modify the Effect of Single Nucleotide Polymorphism Genotypes on Fibrosis in NAFLD.” Hepatol Commun, vol. 5, no. 4, Apr. 2021, pp. 598–607. Pubmed, doi:10.1002/hep4.1668. Full Text
Sadler, Brooke, et al. “Rare and de novo coding variants in chromodomain genes in Chiari I malformation.” Am J Hum Genet, vol. 108, no. 3, Mar. 2021, pp. 530–31. Pubmed, doi:10.1016/j.ajhg.2021.01.014. Full Text
Brummett, Beverly H., et al. “Correction to: 5-HTTLPR and Gender Moderate Changes in Negative Affect Responses to Tryptophan Infusion.” Behav Genet, vol. 51, no. 2, Mar. 2021, p. 163. Pubmed, doi:10.1007/s10519-020-10030-y. Full Text
Brummett, Beverly H., et al. “Correction to: Effects of Environmental Stress and Gender on Associations among Symptoms of Depression and the Serotonin Transporter Gene Linked Polymorphic Region (5-HTTLPR).” Behav Genet, vol. 51, no. 2, Mar. 2021, p. 162. Pubmed, doi:10.1007/s10519-020-10029-5. Full Text
Pages
Wen, Fayuan, et al. “Genome Wide Association Analysis of Iron Overload in the Trans-Omics for Precision Medicine (TOPMed) Sickle Cell Disease Cohorts.” Blood, vol. 136, no. Supplement 1, American Society of Hematology, 2020, pp. 52–52. Crossref, doi:10.1182/blood-2020-142809. Full Text
Baker, C., et al. “IDENTIFICATION OF NOVEL CANDIDATE RISK GENES FOR MYELOMENINGOCELE WITHIN THE GLUCOSE HOMEOSTASIS AND FOLATE AND ONE CARBON METABOLISM NETWORKS.” Journal of Investigative Medicine, vol. 68, BMJ PUBLISHING GROUP, 2020, pp. A145–46. Wos, doi:10.1136/jim-2019-WMRC.336. Full Text
Kachroo, Priyadarshini, et al. “Whole Genome Sequencing Identifies CRISPLD2 as a Lung Function Gene in Children With Asthma.” Chest, vol. 156, no. 6, 2019, pp. 1068–79. Pubmed, doi:10.1016/j.chest.2019.08.2202. Full Text
Bundy, Joseph L., et al. “RNA sequencing of isolated cell populations expressing human APOL1 G2 risk variant reveals molecular correlates of sickle cell nephropathy in zebrafish podocytes.” Plos One, vol. 14, no. 6, 2019, p. e0217042. Pubmed, doi:10.1371/journal.pone.0217042. Full Text
Gelineau-Van Waes, J., et al. “Fumonisin B1 (FB1) and Fingolimod (FTY720): Tortilla Toxin and Oral Therapeutic Target Sphingolipid Pathways during Neural Tube Closure.” Birth Defects Research, vol. 110, no. 9, WILEY, 2018, pp. 730–730.
Smith, Alicia, et al. “Meta-Analysis of DNA Methylation and PTSD in the Psychiatric Genomics Consortium PTSD Epigenetics Workgroup.” Neuropsychopharmacology, vol. 42, NATURE PUBLISHING GROUP, 2017, pp. S120–21.
Grotegut, Chad A., et al. “Single nucleotide polymorphisms in the oxytocin receptor and GRK6 are associated with oxytocin dosing requirements and labor outcomes.” American Journal of Obstetrics and Gynecology, vol. 216, no. 1, MOSBY-ELSEVIER, 2017, pp. S19–S19.
Jacob, Seethal A., et al. “Thrombospondin-1 Polymorphisms Are Associated with Chronic Kidney Disease in Sickle Cell Anemia.” Blood, vol. 128, no. 22, American Society of Hematology, 2016, pp. 2491–2491. Crossref, doi:10.1182/blood.v128.22.2491.2491. Full Text
Xu, Julia Z., et al. “Factors Related to the Progression of Sickle Cell Disease Nephropathy.” Blood, vol. 128, no. 22, American Society of Hematology, 2016, pp. 9–9. Crossref, doi:10.1182/blood.v128.22.9.9. Full Text
Anderson, Blair R., et al. “GWAS Meta-Analysis of Glomerular Filtration Rate in Three Cohorts of Sickle Cell Disease Patients and In Vivo Functional Analysis Reveals Potential Nephropathy Candidate Genes.” Blood, vol. 128, no. 22, American Society of Hematology, 2016, pp. 269–269. Crossref, doi:10.1182/blood.v128.22.269.269. Full Text
Pages
Aung, Tin, et al. “Corrigendum: a common variant mapping to CACNA1A is associated with susceptibility to exfoliation syndrome.” Nat Genet, vol. 47, no. 6, June 2015, p. 689. Pubmed, doi:10.1038/ng0615-689c. Full Text