Allison Elizabeth Ashley-Koch
Professor in Medicine
Overview
Selected Grants
Genetic and Genomics Training Grant awarded by National Institutes of Health (Mentor). 2020 to 2025
NINDS Research Education Programs for Residents and Fellows in Neurosurgery awarded by National Institutes of Health (Mentor). 2009 to 2025
IPA-Allison Ashley-Koch, MIRECC awarded by Durham Veterans Affairs Medical Center (Biostatistician Investigator). 2020 to 2022
IPA-Ashley-Koch, MVP awarded by Durham Veterans Affairs Medical Center (Biostatistician Investigator). 2020 to 2022
Trauma and Genomics Modulate Brain Structure across Common Psychiatric Disorders awarded by National Institutes of Health (Co Investigator). 2017 to 2021
Bioinformatics and Computational Biology Training Program awarded by National Institutes of Health (Mentor). 2005 to 2021
Transfusion Medicine and Hematology awarded by National Institutes of Health (Preceptor). 1975 to 2021
Sharing Comprehensive 'Omics in Sickle Cell Disease Through the NHLBI TOPMed Network awarded by Doris Duke Charitable Foundation, Inc. (Co Investigator). 2019 to 2020
Genetics Training Grant awarded by National Institutes of Health (Mentor). 1979 to 2020
Transcriptomic, therapeutic and genetic investigations of sickle cell nephropathy awarded by National Institutes of Health (Principal Investigator). 2016 to 2020
Pages
Markunas, C. A., et al. “Genetics of the chiari I and II malformations.” The Chiari Malformations, 2020, pp. 289–97. Scopus, doi:10.1007/978-3-030-44862-2_23. Full Text
Markunas, C. A., et al. “Genetics of the Chiari i and II malformations.” The Chiari Malformations, vol. 9781461463696, 2013, pp. 93–101. Scopus, doi:10.1007/978-1-4614-6369-6_7. Full Text
Hillman, Paul, et al. “Identification of novel candidate risk genes for myelomeningocele within the glucose homeostasis/oxidative stress and folate/one-carbon metabolism networks.” Molecular Genetics & Genomic Medicine, vol. 8, no. 11, Nov. 2020, p. e1495. Epmc, doi:10.1002/mgg3.1495. Full Text
Ilboudo, Yann, et al. “Potential causal role of l-glutamine in sickle cell disease painful crises: A Mendelian randomization analysis.” Blood Cells Mol Dis, vol. 86, Sept. 2020, p. 102504. Pubmed, doi:10.1016/j.bcmd.2020.102504. Full Text
Li, Xihao, et al. “Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale.” Nature Genetics, vol. 52, no. 9, Sept. 2020, pp. 969–83. Epmc, doi:10.1038/s41588-020-0676-4. Full Text
Morey, Rajendra A., et al. “Genetic predictors of hippocampal subfield volume in PTSD cases and trauma-exposed controls.” Eur J Psychotraumatol, vol. 11, no. 1, July 2020, p. 1785994. Pubmed, doi:10.1080/20008198.2020.1785994. Full Text
Steffens, D. C., et al. “Genome-wide screen to identify genetic loci associated with cognitive decline in late-life depression.” Int Psychogeriatr, July 2020, pp. 1–9. Pubmed, doi:10.1017/S1041610220001143. Full Text
Worley, Gordon, et al. “Genetic variation in dopamine neurotransmission and motor development of infants born extremely-low-birthweight.” Dev Med Child Neurol, vol. 62, no. 6, June 2020, pp. 750–57. Pubmed, doi:10.1111/dmcn.14383. Full Text
Logue, Mark W., et al. “An epigenome-wide association study of posttraumatic stress disorder in US veterans implicates several new DNA methylation loci.” Clinical Epigenetics, vol. 12, no. 1, Mar. 2020, p. 46. Epmc, doi:10.1186/s13148-020-0820-0. Full Text
Grasby, Katrina L., et al. “The genetic architecture of the human cerebral cortex.” Science (New York, N.Y.), vol. 367, no. 6484, Mar. 2020. Epmc, doi:10.1126/science.aay6690. Full Text Open Access Copy
Hebert, Luke, et al. “Burden of rare deleterious variants in WNT signaling genes among 511 myelomeningocele patients.” Plos One, vol. 15, no. 9, 2020, p. e0239083. Pubmed, doi:10.1371/journal.pone.0239083. Full Text
Nouraie, Mehdi, et al. “Serum albumin is independently associated with higher mortality in adult sickle cell patients: Results of three independent cohorts.” Plos One, vol. 15, no. 8, 2020, p. e0237543. Pubmed, doi:10.1371/journal.pone.0237543. Full Text
Pages
Kachroo, Priyadarshini, et al. “Whole Genome Sequencing Identifies CRISPLD2 as a Lung Function Gene in Children With Asthma.” Chest, vol. 156, no. 6, 2019, pp. 1068–79. Pubmed, doi:10.1016/j.chest.2019.08.2202. Full Text
Bundy, Joseph L., et al. “RNA sequencing of isolated cell populations expressing human APOL1 G2 risk variant reveals molecular correlates of sickle cell nephropathy in zebrafish podocytes.” Plos One, vol. 14, no. 6, 2019, p. e0217042. Pubmed, doi:10.1371/journal.pone.0217042. Full Text
Gelineau-Van Waes, J., et al. “Fumonisin B1 (FB1) and Fingolimod (FTY720): Tortilla Toxin and Oral Therapeutic Target Sphingolipid Pathways during Neural Tube Closure.” Birth Defects Research, vol. 110, no. 9, WILEY, 2018, pp. 730–730.
Smith, Alicia, et al. “Meta-Analysis of DNA Methylation and PTSD in the Psychiatric Genomics Consortium PTSD Epigenetics Workgroup.” Neuropsychopharmacology, vol. 42, NATURE PUBLISHING GROUP, 2017, pp. S120–21.
Grotegut, Chad A., et al. “Single nucleotide polymorphisms in the oxytocin receptor and GRK6 are associated with oxytocin dosing requirements and labor outcomes.” American Journal of Obstetrics and Gynecology, vol. 216, no. 1, MOSBY-ELSEVIER, 2017, pp. S19–S19.
Jacob, Seethal A., et al. “Thrombospondin-1 Polymorphisms Are Associated with Chronic Kidney Disease in Sickle Cell Anemia.” Blood, vol. 128, no. 22, American Society of Hematology, 2016, pp. 2491–2491. Crossref, doi:10.1182/blood.v128.22.2491.2491. Full Text
Xu, Julia Z., et al. “Factors Related to the Progression of Sickle Cell Disease Nephropathy.” Blood, vol. 128, no. 22, American Society of Hematology, 2016, pp. 9–9. Crossref, doi:10.1182/blood.v128.22.9.9. Full Text
Anderson, Blair R., et al. “GWAS Meta-Analysis of Glomerular Filtration Rate in Three Cohorts of Sickle Cell Disease Patients and In Vivo Functional Analysis Reveals Potential Nephropathy Candidate Genes.” Blood, vol. 128, no. 22, American Society of Hematology, 2016, pp. 269–269. Crossref, doi:10.1182/blood.v128.22.269.269. Full Text
Smith, Alicia, et al. “Epigenome-Wide Association of PTSD from Heterogeneous Cohorts with a Common Multi-Site Analysis Pipeline.” Biological Psychiatry, vol. 79, no. 9, ELSEVIER SCIENCE INC, 2016, pp. 164S-165S.
Morey, Rajendra A., et al. “Genome-Wide Association of Neuroimaging Phenotypes in PTSD at Multiple Sites.” Biological Psychiatry, vol. 79, no. 9, ELSEVIER SCIENCE INC, 2016, pp. 165S-165S.
Pages
Aung, Tin, et al. “Corrigendum: a common variant mapping to CACNA1A is associated with susceptibility to exfoliation syndrome.” Nat Genet, vol. 47, no. 6, June 2015, p. 689. Pubmed, doi:10.1038/ng0615-689c. Full Text