Brenda Lee Plassman
Professor in Psychiatry and Behavioral Sciences
1) Epidemiological studies to examine the prevalence and incidence of dementia and cognitive impairment, not dementia (CIND)
2) Studies examining risk and protective factors for dementia and CIND
3) Behavioral genetics of aging and dementia with an emphasis on twin studies
4) Long term outcomes of traumatic brain injury
5) Oral health and cognition in later life
Duke Creating ADRD Researchers for the Next Generation - Stimulating Access to Research in Residency Program (CARiNG-StARR)" awarded by National Institutes of Health (Preceptor). 2020 to 2023
NC Registry for Brain Health Phase 2 awarded by State of North Carolina (Co Investigator). 2019 to 2021
Caregivers' Reactions and Experience: Imaging Dementia-Evidence for Amyloid Scanning-CARE IDEAS awarded by Brown University (Co Investigator). 2017 to 2021
Life Course Process of Alzheimer's Disease: Sex Difference and Biosocial Mechanisms awarded by University of North Carolina - Chapel Hill (Principal Investigator). 2017 to 2021
Decision Making for Cardiovascular Therapy in Adults with Mild Cognitive Impairment awarded by University of Michigan (Principal Investigator). 2016 to 2021
Alzheimer's Disease, Genes, and Pesticide Use in the Agricultural Health Study awarded by National Institutes of Health (Principal Investigator). 2014 to 2021
National Health and Aging Trends Study awarded by Johns Hopkins University (Principal Investigator). 2019 to 2021
VRFCAT Supplement awarded by VeraSci (Principal Investigator). 2019 to 2021
Validation of a Performance Based Measure of Functioning in MCI and Early AD (VRFCAT) awarded by VeraSci (Principal Investigator). 2018 to 2021
Pesticides, Olfaction, and Prodromal Neurodegeneration Among US Farmers awarded by Michigan State University (Principal Investigator). 2019 to 2021
Cocroft, Shelytia, et al. “Racially diverse participant registries to facilitate the recruitment of African Americans into presymptomatic Alzheimer's disease studies.” Alzheimers Dement, June 2020. Pubmed, doi:10.1002/alz.12048. Full Text
Lawrence, Karen A., et al. “Risk and protective factors of dementia among adults with post-traumatic stress disorder: a systematic review protocol.” Bmj Open, vol. 10, no. 6, June 2020, p. e035517. Pubmed, doi:10.1136/bmjopen-2019-035517. Full Text
Casanova, Ramon, et al. “Investigating Predictors of Cognitive Decline Using Machine Learning.” J Gerontol B Psychol Sci Soc Sci, vol. 75, no. 4, Mar. 2020, pp. 733–42. Pubmed, doi:10.1093/geronb/gby054. Full Text
Jutkowitz, Eric, et al. “Willingness to Undergo a Risky Treatment to Improve Cognition Among Persons With Cognitive Impairment Who Received an Amyloid PET Scan.” Alzheimer Dis Assoc Disord, vol. 34, no. 1, Jan. 2020, pp. 1–9. Pubmed, doi:10.1097/WAD.0000000000000338. Full Text
James, Hailey J., et al. “How Accurately Do Patients and Their Care Partners Report Results of Amyloid-β PET Scans for Alzheimer's Disease Assessment?” J Alzheimers Dis, vol. 74, no. 2, 2020, pp. 625–36. Pubmed, doi:10.3233/JAD-190922. Full Text
Gatz, Margaret, et al. “The NAS-NRC Twin Registry and Duke Twins Study of Memory in Aging: An Update.” Twin Res Hum Genet, vol. 22, no. 6, Dec. 2019, pp. 757–60. Pubmed, doi:10.1017/thg.2019.45. Full Text
Lutz, Michael W., et al. “Analysis of pleiotropic genetic effects on cognitive impairment, systemic inflammation, and plasma lipids in the Health and Retirement Study.” Neurobiol Aging, vol. 80, Aug. 2019, pp. 173–86. Pubmed, doi:10.1016/j.neurobiolaging.2018.10.028. Full Text
Anderson, Ruth A., et al. “Working together to learn new oral hygiene techniques: Pilot of a carepartner-assisted intervention for persons with cognitive impairment.” Geriatr Nurs, vol. 40, no. 3, May 2019, pp. 269–76. Pubmed, doi:10.1016/j.gerinurse.2018.11.002. Full Text
Kuchibhatla, Maragatha, et al. “The association between neighborhood socioeconomic status, cardiovascular and cerebrovascular risk factors, and cognitive decline in the Health and Retirement Study (HRS).” Aging Ment Health, Apr. 2019, pp. 1–8. Pubmed, doi:10.1080/13607863.2019.1594169. Full Text
Knodt, Annchen R., et al. “Effects of pioglitazone on mnemonic hippocampal function: A blood oxygen level-dependent functional magnetic resonance imaging study in elderly adults.” Alzheimers Dement (N Y), vol. 5, 2019, pp. 254–63. Pubmed, doi:10.1016/j.trci.2019.05.004. Full Text
Reale, Bailey K., et al. “Reasons Pre-Existing Mild Cognitive Impairment May Influence Physician Recommendations for Stroke and Heart Attack Treatments.” Stroke, vol. 50, LIPPINCOTT WILLIAMS & WILKINS, 2019.
Hall, Jennifer, et al. “Utility of NPI Scores Predicting Progression of CIND to Dementia.” American Journal of Geriatric Psychiatry, vol. 20, no. 3, ELSEVIER SCIENCE INC, 2012, pp. S86–87.
Plassman, Brenda L., et al. “P4-137 Alzheimer's disease in the NAS-NRC twin registry of WWII veterans.” Neurobiology of Aging, vol. 25, Elsevier BV, 2004, pp. S514–S514. Crossref, doi:10.1016/s0197-4580(04)81695-6. Full Text
Browndyke, Jeffrey N., et al. “P1-109 Verbal recognition memory differences in Alzheimer's disease and vascular dementia: examining recognition response characteristics independent of dementia severity.” Neurobiology of Aging, vol. 25, Elsevier BV, 2004, pp. S126–S126. Crossref, doi:10.1016/s0197-4580(04)80423-8. Full Text
Hening, W. A., et al. “Prevalence of restless legs symptoms in an elderly American veteran cohort.” Sleep, vol. 26, AMER ACADEMY SLEEP MEDICINE, 2003, pp. A338–A338.
Steffens, D. C., et al. “A twin study of late-onset depression and APOE e4 as risk factors for dementia.” American Journal of Geriatric Psychiatry, vol. 4, no. 4, AMER PSYCHIATRIC ASSOCIATION, 1996, pp. 379–80.