Cagla Eroglu

Cagla Eroglu

Associate Professor of Cell Biology

External Address: 
333A Nanaline Duke Bldg, Durham, NC 27710
Internal Office Address: 
Duke Box 3709, Durham, NC 27710


Education & Training

  • Ph.D., Ruprecht Karl University (Germany) 2002

Selected Grants

Genetic and Genomics Training Grant awarded by National Institutes of Health (Mentor). 2020 to 2025

Neurobiology Training Program awarded by National Institutes of Health (Mentor). 2019 to 2024

Heat Shock Factors and Protein Misfolding Disease awarded by National Institutes of Health (Principal Investigator). 2018 to 2023

Control of Astrocyte Development and Astrocyte-Synapse Interactions awarded by National Institutes of Health (Principal Investigator). 2018 to 2023

How do Astrocytes Control Inhibitory Synapse Formation and Function? awarded by Pew Charitable Trusts Latin American Fellows Prog (Principal Investigator). 2018 to 2022

Training Program in Developmental and Stem Cell Biology awarded by National Institutes of Health (Mentor). 2001 to 2022

Control of Astrocyte Morphogenesis and Synaptogenesis by Astrocytic Neuroligins awarded by National Institutes of Health (Principal Investigator). 2019 to 2022

Control of Astrocyte Function by Parkinsonism Gene LRRK2 awarded by Michael J. Fox Foundation for Parkinson's Research (Principal Investigator). 2019 to 2021

CZI Neurodegeneration Community Projects awarded by Chan Zuckerberg Initiative (Principal Investigator). 2019 to 2021


Ostrovskaya, Olga I., et al. “Developmental onset of enduring long-term potentiation in mouse hippocampus.Hippocampus, Sept. 2020. Pubmed, doi:10.1002/hipo.23257. Full Text

Risher, William Christopher, and Cagla Eroglu. “Emerging roles for α2δ subunits in calcium channel function and synaptic connectivity.Curr Opin Neurobiol, vol. 63, Aug. 2020, pp. 162–69. Pubmed, doi:10.1016/j.conb.2020.04.007. Full Text

Luo, Lin, et al. “Optimizing Nervous System-Specific Gene Targeting with Cre Driver Lines: Prevalence of Germline Recombination and Influencing Factors.Neuron, vol. 106, no. 1, Apr. 2020, pp. 37-65.e5. Pubmed, doi:10.1016/j.neuron.2020.01.008. Full Text

Burrus, Caley J., et al. “Striatal Projection Neurons Require Huntingtin for Synaptic Connectivity and Survival.Cell Reports, vol. 30, no. 3, Jan. 2020, pp. 642-657.e6. Epmc, doi:10.1016/j.celrep.2019.12.069. Full Text

Park, Jieun, et al. “Lysosome-Rich Enterocytes Mediate Protein Absorption in the Vertebrate Gut.Dev Cell, vol. 51, no. 1, Oct. 2019, pp. 7-20.e6. Pubmed, doi:10.1016/j.devcel.2019.08.001. Full Text

Sakers, Kristina, and Cagla Eroglu. “Control of neural development and function by glial neuroligins.Curr Opin Neurobiol, vol. 57, Aug. 2019, pp. 163–70. Pubmed, doi:10.1016/j.conb.2019.03.007. Full Text

Baldwin, Katherine T., and Cagla Eroglu. “Astrocytes "Chordinate" Synapse Maturation and Plasticity.Neuron, vol. 100, no. 5, Dec. 2018, pp. 1010–12. Pubmed, doi:10.1016/j.neuron.2018.11.027. Full Text

Risher, W. Christopher, et al. “Thrombospondin receptor α2δ-1 promotes synaptogenesis and spinogenesis via postsynaptic Rac1.J Cell Biol, vol. 217, no. 10, Oct. 2018, pp. 3747–65. Pubmed, doi:10.1083/jcb.201802057. Full Text

Koh, Sehwon, et al. “Subretinal Human Umbilical Tissue-Derived Cell Transplantation Preserves Retinal Synaptic Connectivity and Attenuates Müller Glial Reactivity.J Neurosci, vol. 38, no. 12, Mar. 2018, pp. 2923–43. Pubmed, doi:10.1523/JNEUROSCI.1532-17.2018. Full Text

E, Lezi, et al. “An Antimicrobial Peptide and Its Neuronal Receptor Regulate Dendrite Degeneration in Aging and Infection.Neuron, vol. 97, no. 1, Jan. 2018, pp. 125-138.e5. Epmc, doi:10.1016/j.neuron.2017.12.001. Full Text Open Access Copy


Eroglu, C. “Control of synaptic connectivity by astrocytes.” Glia, vol. 65, WILEY, 2017, pp. E76–77.

Eroglu, C. “Control of synaptic connectivity and homeostasis by astrocytes.” Journal of Neurochemistry, vol. 134, WILEY-BLACKWELL, 2015, pp. 43–43.

Gunnersen, J., et al. “SEZ6 binds the analgesic target alpha 2 delta and contributes to neuropathic pain plasticity.” Journal of Neurochemistry, vol. 134, WILEY-BLACKWELL, 2015, pp. 141–141.

Koh, Sehwon, et al. “Human umbilical tissue-derived cells (hUTC) promote synapse formation and neurite outgrowth via Thrombospondin family proteins: A potential mechanism for hUTC-based therapy in retinal-degenerative diseases.” Investigative Ophthalmology & Visual Science, vol. 56, no. 7, ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2015.

Eroglu, C. “Astrocyes orchestrate dendritic spine formation and maturation.” Journal of Neurochemistry, vol. 125, WILEY-BLACKWELL, 2013, pp. 29–29.

Singh, S. K., et al. “How do astrocyte secreted factors Hevin and SPARC control excitatory synaptogenesis in the CNS?Journal of Neurochemistry, vol. 125, WILEY-BLACKWELL, 2013, pp. 8–8.