Christina S. Meade
Associate Professor in Psychiatry and Behavioral Sciences
Dr. Meade’s domestic research program focuses on predictors of HIV risk behavior in adults with substance use and psychiatric disorders, and the relationship between neuropsychiatric conditions and continued risk behavior in HIV-positive adults. She is particularly interested in how drug addiction and HIV infection impact executive functions, such as decision making, that lead individuals to engage in risky behaviors. Many of her current projects incorporate MRI to isolate the effects of addiction and HIV on both brain function and structure. Dr. Meade is also interested in the development of evidence-based treatments to improve cognitive functioning and reduce risk behaviors among drug users.
Given that most people infected or affected by HIV/AIDS live in Sub-Saharan Africa, Dr. Meade’s international research program is based in South Africa. The Western Cape has experienced a dramatic increase in methamphetamine use since the early 2000s, and there is concern that it may further fuel the HIV epidemic in this country. Current projects focus on characterizing drug addiction and HIV risk behaviors in this understudied group, both in in community and treatment settings, and ultimately increasing uptake of HIV services to improve health outcomes and reduce the continued spread of HIV.
Towe, Sheri L., et al. “Reciprocal Influences of HIV and Cannabinoids on the Brain and Cognitive Function.” J Neuroimmune Pharmacol, vol. 15, no. 4, Dec. 2020, pp. 765–79. Pubmed, doi:10.1007/s11481-020-09921-y. Full Text
Lee, Jared, et al. “Tryptophan degradation is associated with risk-taking propensity in methamphetamine users with treated HIV infection.” J Neurovirol, vol. 26, no. 5, Oct. 2020, pp. 779–84. Pubmed, doi:10.1007/s13365-020-00841-4. Full Text
Meade, Christina S., et al. “HIV Prevalence and Associated Risks in a Respondent-Driven Sample of Illicit Stimulant Users in a Southern United States City.” Aids Behav, vol. 24, no. 8, Aug. 2020, pp. 2336–46. Pubmed, doi:10.1007/s10461-020-02793-6. Full Text
Bell, Ryan P., et al. “Neural sensitivity to risk in adults with co-occurring HIV infection and cocaine use disorder.” Cogn Affect Behav Neurosci, vol. 20, no. 4, Aug. 2020, pp. 859–72. Pubmed, doi:10.3758/s13415-020-00806-4. Full Text
Patel, Puja, et al. “Problematic alcohol use among fathers in Kenya: Poverty, people, and practices as barriers and facilitators to help acceptance.” Int J Drug Policy, vol. 75, Jan. 2020, p. 102576. Pubmed, doi:10.1016/j.drugpo.2019.10.003. Full Text
Meade, Christina S., et al. “Cocaine-related alterations in fronto-parietal gray matter volume correlate with trait and behavioral impulsivity.” Drug Alcohol Depend, vol. 206, Jan. 2020, p. 107757. Pubmed, doi:10.1016/j.drugalcdep.2019.107757. Full Text
Meade, Christina S., et al. “Synergistic effects of marijuana abuse and HIV infection on neural activation during a cognitive interference task.” Addict Biol, vol. 24, no. 6, Nov. 2019, pp. 1235–44. Pubmed, doi:10.1111/adb.12678. Full Text
Skalski, Linda M., et al. “Sexual Orientation, Religious Coping, and Drug Use in a Sample of HIV-Infected African-American Men Living in the Southern USA.” J Relig Health, vol. 58, no. 4, Aug. 2019, pp. 1368–81. Pubmed, doi:10.1007/s10943-019-00791-0. Full Text
Hobkirk, Andréa L., et al. “Reward and executive control network resting-state functional connectivity is associated with impulsivity during reward-based decision making for cocaine users.” Drug Alcohol Depend, vol. 194, Jan. 2019, pp. 32–39. Pubmed, doi:10.1016/j.drugalcdep.2018.09.013. Full Text
Towe, Sheri L., et al. “A Comparison of Motivations for Marijuana Use in HIV-Positive and HIV-Negative Adults.” Aids Behav, vol. 22, no. 9, Sept. 2018, pp. 2807–14. Pubmed, doi:10.1007/s10461-018-2123-4. Full Text