Christine Elizabeth Marx

Christine Elizabeth Marx

Professor of Psychiatry and Behavioral Sciences

External Address: 
VA Medical Ctr 116 A, 508 Fulton St, Durham, NC 27705
Internal Office Address: 
Box 3862 Med Ctr, DUMC, Durham, NC 27710


Education & Training

  • M.D., Duke University 1992

Selected Grants

Duke CTSA (TL1) awarded by National Institutes of Health (Mentor). 2018 to 2023

Clinical Medication Development for Bipolar Disorder and Alcohol Use Disorders awarded by (Principal Investigator). 2018 to 2021

IPA - Susan Helene O'Loughlin awarded by (Principal Investigator). 2019 to 2021

IPA - Lawrence Shampine awarded by (Principal Investigator). 2019 to 2021

IPA - Brian Thomas Cuffe awarded by (Principal Investigator). 2019 to 2021

IPA - Patricia Resick awarded by (Principal Investigator). 2020

IPA - Jason Kilts awarded by (Principal Investigator). 2019 to 2020

IPA - Patricia Resick awarded by (Principal Investigator). 2019 to 2020

IPA - Larry Allen Tupler awarded by (Principal Investigator). 2018 to 2020

IPA - Rachel Phillips awarded by (Principal Investigator). 2019


Massing, M. W., et al. “Applications of proteomics to nerve regeneration research.” Neuroproteomics, 2009, pp. 289–313.

Morey, Rajendra A., et al. “Neural correlates of conceptual-level fear generalization in posttraumatic stress disorder.Neuropsychopharmacology, vol. 45, no. 8, July 2020, pp. 1380–89. Pubmed, doi:10.1038/s41386-020-0661-8. Full Text

Rauch, Sheila A. M., et al. “Neuroendocrine biomarkers of prolonged exposure treatment response in military-related PTSD.Psychoneuroendocrinology, vol. 119, June 2020, p. 104749. Pubmed, doi:10.1016/j.psyneuen.2020.104749. Full Text

Kinzel, Philipp, et al. “Serum Neurosteroid Levels Are Associated With Cortical Thickness in Individuals Diagnosed With Posttraumatic Stress Disorder and History of Mild Traumatic Brain Injury.Clin Eeg Neurosci, Mar. 2020, p. 1550059420909676. Pubmed, doi:10.1177/1550059420909676. Full Text

Logue, Mark W., et al. “An epigenome-wide association study of posttraumatic stress disorder in US veterans implicates several new DNA methylation loci.Clin Epigenetics, vol. 12, no. 1, Mar. 2020, p. 46. Pubmed, doi:10.1186/s13148-020-0820-0. Full Text

Naylor, Jennifer C., et al. “Effect of Pregnenolone vs Placebo on Self-reported Chronic Low Back Pain Among US Military Veterans: A Randomized Clinical Trial.Jama Netw Open, vol. 3, no. 3, Mar. 2020, p. e200287. Pubmed, doi:10.1001/jamanetworkopen.2020.0287. Full Text

Morey, Rajendra A., et al. “Amygdala Nuclei Volume and Shape in Military Veterans With Posttraumatic Stress Disorder.Biol Psychiatry Cogn Neurosci Neuroimaging, vol. 5, no. 3, Mar. 2020, pp. 281–90. Pubmed, doi:10.1016/j.bpsc.2019.11.016. Full Text

Rakesh, Gopalkumar, et al. “Resilience as a translational endpoint in the treatment of PTSD.Mol Psychiatry, vol. 24, no. 9, Sept. 2019, pp. 1268–83. Pubmed, doi:10.1038/s41380-019-0383-7. Full Text

Naylor, Jennifer C., et al. “Pain Intensity and Pain Interference in Male and Female Iraq/Afghanistan-era Veterans.Womens Health Issues, vol. 29 Suppl 1, June 2019, pp. S24–31. Pubmed, doi:10.1016/j.whi.2019.04.015. Full Text

Shura, Robert D., et al. “Relationship between traumatic brain injury history and recent suicidal ideation in Iraq/Afghanistan-era veterans.Psychol Serv, vol. 16, no. 2, May 2019, pp. 312–20. Pubmed, doi:10.1037/ser0000208. Full Text

Bomyea, Jessica, et al. “Associations between neuropsychiatric and health status outcomes in individuals with probable mTBI.Psychiatry Res, vol. 272, Feb. 2019, pp. 531–39. Pubmed, doi:10.1016/j.psychres.2018.12.021. Full Text


Morey, Rajendra A., et al. “Assessment of Myelin Compromise in Mild Traumatic Brain Injury with Quantitative Susceptibility Mapping.” Biological Psychiatry, vol. 77, no. 9, ELSEVIER SCIENCE INC, 2015, pp. 40S-40S.

Marx, Christine E. “Neurosteroids as Novel Therapeutics and Biomarker Candidates in Schizophrenia and PTSD.” Neuropsychopharmacology, vol. 38, NATURE PUBLISHING GROUP, 2013, pp. S37–38.

Wong, Peiyan, et al. “Pregnenolone Rescues Schizophrenia-Like Behavior in Dopamine Transporter Knockout Mice.” Biological Psychiatry, vol. 73, no. 9, ELSEVIER SCIENCE INC, 2013, pp. 115S-116S.

Sripada, Rebecca K., et al. “Neuroactive Steroids Enhance Activation of Emotion Regulation Brain Circuits.” Biological Psychiatry, vol. 71, no. 8, ELSEVIER SCIENCE INC, 2012, pp. 177S-178S.

Marx, Christine E. “Proof-of-Concept Randomized Controlled Trial with Pregnenolone in Mild Traumatic Brain Injury.” Biological Psychiatry, vol. 67, no. 9, ELSEVIER SCIENCE INC, 2010, pp. 22S-22S.

Eggleston, A. M., et al. “Alcohol use among OEF-OIF veterans with and without posttraumatic stress disorder.” Alcoholism Clinical and Experimental Research, vol. 32, no. 6, 2008, pp. 75A-75A.

Nayllor, Jennifer C., et al. “L-serine predicts self-reported pain in female OEF/OIF veterans.” Biological Psychiatry, vol. 63, no. 7, 2008, pp. 218S-218S.

Payne, Victoria M., et al. “Neuroactive steroids are related to psychiatric symptoms in veterans returning from iraq and Afghanistan.” Biological Psychiatry, vol. 61, no. 8, 2007, pp. 130S-131S.

Naylor, Jennifer C., et al. “Cerebrospinal fluid DHEA levels are elevated in Alzheimer's disease, related to neuropathological disease stage, and correlated with brain DHEA levels.” Biological Psychiatry, vol. 61, no. 8, ELSEVIER SCIENCE INC, 2007, pp. 142S-142S.