F Joseph McClernon
Professor in Psychiatry & Behavioral Sciences
Overview
Joe McClernon, Ph.D. is Professor and Director of the Addiction Division in the Department of Psychiatry and Behavioral Sciences and is Founder/Director of the Center for Addiction Science and Technology (CfAST) at the Duke University Medical Center. He earned a Ph.D. in clinical psychology in 2001 from Southern Illinois University-Carbondale and completed a postdoctoral fellowship at Duke in 2002. Joe’s research is focused on increasing our understanding of tobacco and other addictions, developing new and more effective interventions to treat substance abuse, and informing the FDA’s regulation of tobacco products. He makes use of behavioral pharmacology, neuroimaging, epidemiology and clinical trial approaches in his work. He has led groundbreaking research on: the influence of drug-associated environments on drug use, relapse, and treatment; tobacco use disparities among individuals with comorbid psychiatric (e.g. ADHD) and health (e.g. HIV) problems; the role of nicotine in smoking behavior; and the evaluation of potential FDA tobacco regulatory actions. He has been continuously NIH- and FDA-funded since 2002. He has authored over 130 peer-reviewed publications, has one patent, has served as Chair of NIH grant review panels, and is recipient of numerous awards including the SRNT Jarvik-Russell New Investigator Award.
Selected Grants
Duke CTSA (KL2) awarded by National Institutes of Health (Mentor). 2018 to 2023
Duke CTSA (TL1) awarded by National Institutes of Health (Mentor). 2018 to 2023
Mobile health interventions for varenicline adherence among HIV-positive smokers awarded by National Institutes of Health (Mentor). 2017 to 2022
Mobile health interventions for varenicline adherence among HIV-positive smokers awarded by National Institutes of Health (Mentor). 2017 to 2022
Impact of new standards for tobacco products among dual e-cigarette/combusted cigarette users awarded by National Institutes of Health (Principal Investigator). 2019 to 2022
Nicotine Withdrawal and Reward Processing: Connecting Neurobiology to Real-World Behavior awarded by National Institutes of Health (Mentor). 2017 to 2022
Project 2: Evaluating New Nicotine Standards for Cigarettes - Supplement awarded by University of Minnesota (Principal Investigator). 2017 to 2022
Early-phase Studies of a Tailored Evidence-Based Smoking Cessation mHealth App for Persons Living with HIV awarded by National Institutes of Health (Co Investigator). 2019 to 2021
Targeting reward dysfunction as a mechanism to improve smoking cessation awarded by National Institutes of Health (Mentor). 2016 to 2021
Deep learning-based image analysis for assessing real-time smoking risk awarded by National Institutes of Health (Principal Investigator). 2018 to 2020
Pages
Kollins, S. H., and F. J. McClernon. “ADHD and smoking.” Attention-Deficit Hyperactivity Disorder in Adults and Children, 2015, pp. 327–42. Scopus, doi:10.1017/CBO9781139035491.027. Full Text
Pacek, Lauren R., et al. “Graphic Warning Labels Affect Hypothetical Cigarette Purchasing Behavior among Smokers Living with HIV..” Int J Environ Res Public Health, vol. 16, no. 18, Sept. 2019. Pubmed, doi:10.3390/ijerph16183380. Full Text
Engelhard, Matthew M., et al. “Identifying Smoking Environments From Images of Daily Life With Deep Learning..” Jama Netw Open, vol. 2, no. 8, Aug. 2019. Pubmed, doi:10.1001/jamanetworkopen.2019.7939. Full Text
Cassidy, Rachel N., et al. “Age Moderates Smokers' Subjective Response to Very-Low Nicotine Content Cigarettes: Evidence from a Randomized Controlled Trial..” Nicotine Tob Res, vol. 21, no. 7, June 2019, pp. 962–69. Pubmed, doi:10.1093/ntr/nty079. Full Text
Vilardaga, Roger, et al. “Mobile Applications for the Treatment of Tobacco Use and Dependence.” Current Addiction Reports, vol. 6, no. 2, Springer Science and Business Media LLC, June 2019, pp. 86–97. Crossref, doi:10.1007/s40429-019-00248-0. Full Text Open Access Copy
Maynard, Olivia M., et al. “Using Neuroscience to Inform Tobacco Control Policy..” Nicotine Tob Res, vol. 21, no. 6, May 2019, pp. 739–46. Pubmed, doi:10.1093/ntr/nty057. Full Text
Addicott, Merideth A., et al. “The Effects of Nicotine and Tobacco Use on Brain Reward Function: Interaction With Nicotine Dependence Severity..” Nicotine Tob Res, vol. 21, no. 6, May 2019, pp. 764–71. Pubmed, doi:10.1093/ntr/nty059. Full Text
Denlinger-Apte, Rachel L., et al. “Correlates of support for a nicotine-reduction policy in smokers with 6-week exposure to very low nicotine cigarettes..” Tob Control, vol. 28, no. 3, May 2019, pp. 352–55. Pubmed, doi:10.1136/tobaccocontrol-2018-054622. Full Text
Pacek, Lauren R., et al. “A Conceptual Framework for Understanding Multiple Tobacco Product Use and the Impact of Regulatory Action..” Nicotine Tob Res, vol. 21, no. 3, Feb. 2019, pp. 268–77. Pubmed, doi:10.1093/ntr/nty129. Full Text
Conklin, Cynthia A., et al. “Combined Smoking Cues Enhance Reactivity and Predict Immediate Subsequent Smoking..” Nicotine Tob Res, vol. 21, no. 2, Jan. 2019, pp. 241–48. Pubmed, doi:10.1093/ntr/nty009. Full Text
Chen, Menglan, et al. “Longitudinal stability in cigarette smokers of urinary biomarkers of exposure to the toxicants acrylonitrile and acrolein..” Plos One, vol. 14, no. 1, 2019. Pubmed, doi:10.1371/journal.pone.0210104. Full Text
Pages
Sweitzer, Maggie M., et al. “FEASIBILITY AND PRELIMINARY EFFECTS OF INCORPORATING SMOKING-RELATED CONTEXTS INTO AN EXTINCTION-BASED CESSATION THERAPY.” Annals of Behavioral Medicine, vol. 52, OXFORD UNIV PRESS INC, 2018, pp. S381–S381.
Oliver, Jason, et al. “Increased Activation in Precuneus and Parahippocampus When Smokers View Tobacco Retail Outlets: Results of a GPS plus fMRI 'Community Neuroscience' Study.” Neuropsychopharmacology, vol. 42, NATURE PUBLISHING GROUP, 2017, pp. S325–26.
Giovacchini, Coral X., et al. “Use and Perceived Risk of Electronic Cigarettes Among North Carolina Middle and High School Students..” N C Med J, vol. 78, no. 1, 2017, pp. 7–13. Pubmed, doi:10.18043/ncm.78.1.7. Full Text
Ouyang, R. W., et al. “If you see something, swipe towards it: Crowdsourced event localization using smartphones.” Ubicomp 2013 Proceedings of the 2013 Acm International Joint Conference on Pervasive and Ubiquitous Computing, 2013, pp. 23–32. Scopus, doi:10.1145/2493432.2493455. Full Text
Vrana, Scott R., et al. “THE EFFECT OF SMOKING ON THE ACOUSTIC STARTLE RESPONSE AND PREPULSE INHIBITION PREDICTS A SUCCESSFUL QUIT ATTEMPT IN SMOKERS WITH AND WITHOUT POST-TRAUMATIC STRESS DISORDER.” Psychophysiology, vol. 50, WILEY-BLACKWELL, 2013, pp. S32–S32.
McClernon, Francis J., et al. “COMBINED EMA AND GPS FOR ASSESSING THE SPATIAL DISTRIBUTION OF SMOKING BEHAVIOR: A PROOF OF CONCEPT STUDY.” Annals of Behavioral Medicine, vol. 45, SPRINGER, 2013, pp. S93–S93.
Lee, Hyoung S., et al. “RELATIONSHIP BETWEEN CHANGES IN IMPLICIT ATTITUDES TOWARD SMOKING AND SMOKING CESSATION.” Annals of Behavioral Medicine, vol. 45, SPRINGER, 2013, pp. S93–S93.
Bidwell, L. Cinnamon, et al. “Genotype and ADHD symptoms interact to predict adolescents' early smoking experiences in an epidemiological sample.” Behavior Genetics, vol. 41, no. 6, SPRINGER, 2011, pp. 893–893.
Rose, Jed E., et al. “Repetitive Transcranial Magnetic Stimulation (rTMS) of the Superior Frontal Gyrus Modulates Craving for Cigarettes.” Biological Psychiatry, vol. 69, no. 9, ELSEVIER SCIENCE INC, 2011, pp. 277S-278S.
Szabo, Steven T., et al. “Translational Development of Novel Pharmacotherapeutic Strategies for Psychostimulant Dependence.” Biological Psychiatry, vol. 67, no. 9, ELSEVIER SCIENCE INC, 2010, pp. 88S-88S.