Jeffrey Nicholas Browndyke

Jeffrey Nicholas Browndyke

Associate Professor of Psychiatry and Behavioral Sciences

External Address: 
Durham VA Box 116-A, 508 Fulton St, Durham, NC 27705
Internal Office Address: 
Durham VA Box 116-A, 508 Fulton St, Durham, NC 27710
Phone: 
919.286.0411

Overview

Dr. Browndyke is an Associate Professor of Behavioral Health & Neurosciences in the Department of Psychiatry & Behavioral Sciences.  He has a secondary appointment as Assistant Professor of Cardiovascular & Thoracic Surgery.

Dr. Browndyke's research interests involve the use of advanced neurocognitive and neuroimaging techniques for perioperative contributions to delirium and later dementia risk, monitoring of late-life neuropathological disease progression, and intervention/treatment outcomes.  His research also involves novel telehealth methods for remote neurocognitive evaluation and implementation of non-invasive neuromodulatory techniques to assist in postoperative recovery and dementia risk reduction.

Dr. Browndyke's clinical expertise is focused upon geriatric neuropsychology with an emphasis in the assessment, diagnosis, and treatment of dementia and related disorders in adults and US veteran patient populations.

Education & Training

  • Psychology Fellowship Program, Psychology, Brown University, Warren Alpert Medical School 2000 - 2003

  • Ph.D., Louisiana State University, Baton Rouge 2001

  • B.S., The University of Memphis 1993

Selected Grants

Neurocognition & Greater Maintenance of Sinus Rhythm in AF (NOGGIN AF) awarded by National Institutes of Health (Co Investigator). 2021 to 2026

Bertrand, Philippe B., et al. “Progression of Tricuspid Regurgitation After Surgery for Ischemic Mitral Regurgitation.J Am Coll Cardiol, vol. 77, no. 6, Feb. 2021, pp. 713–24. Pubmed, doi:10.1016/j.jacc.2020.11.066. Full Text Open Access Copy

Terrando, Niccolò, et al. “Immunomodulatory lipid mediator profiling of cerebrospinal fluid following surgery in older adults.Sci Rep, vol. 11, no. 1, Feb. 2021, p. 3047. Pubmed, doi:10.1038/s41598-021-82606-5. Full Text

Berger, Miles, et al. “APOE4 Copy Number-Dependent Proteomic Changes in the Cerebrospinal Fluid.J Alzheimers Dis, vol. 79, no. 2, 2021, pp. 511–30. Pubmed, doi:10.3233/JAD-200747. Full Text

VanDusen, Keith W., et al. “Cerebrospinal Fluid Proteome Changes in Older Non-Cardiac Surgical Patients with Postoperative Cognitive Dysfunction.J Alzheimers Dis, vol. 80, no. 3, 2021, pp. 1281–97. Pubmed, doi:10.3233/JAD-201544. Full Text Open Access Copy

Oyeyemi, Deborah M., et al. “Relationship Between Depression/Anxiety and Cognitive Function Before and 6 Weeks After Major Non-Cardiac Surgery in Older Adults.J Geriatr Psychiatry Neurol, Dec. 2020, p. 891988720978791. Pubmed, doi:10.1177/0891988720978791. Full Text

Nobuhara, Chloe K., et al. “A protocol to reduce self-reported pain scores and adverse events following lumbar punctures in older adults.J Neurol, vol. 267, no. 7, July 2020, pp. 2002–06. Pubmed, doi:10.1007/s00415-020-09797-1. Full Text

Ferket, Bart S., et al. “Cost-effectiveness of coronary artery bypass grafting plus mitral valve repair versus coronary artery bypass grafting alone for moderate ischemic mitral regurgitation.J Thorac Cardiovasc Surg, vol. 159, no. 6, June 2020, pp. 2230-2240.e15. Pubmed, doi:10.1016/j.jtcvs.2019.06.040. Full Text

Lala, Anuradha, et al. “Risk for non-home discharge following surgery for ischemic mitral valve disease.J Thorac Cardiovasc Surg, Mar. 2020. Pubmed, doi:10.1016/j.jtcvs.2020.02.084. Full Text

Blumenthal, James A., et al. “Longer Term Effects of Diet and Exercise on Neurocognition: 1-Year Follow-up of the ENLIGHTEN Trial.J Am Geriatr Soc, vol. 68, no. 3, Mar. 2020, pp. 559–68. Pubmed, doi:10.1111/jgs.16252. Full Text

Smith, Patrick J., et al. “Metabolic and Neurocognitive Changes Following Lifestyle Modification: Examination of Biomarkers from the ENLIGHTEN Randomized Clinical Trial.J Alzheimers Dis, vol. 77, no. 4, 2020, pp. 1793–803. Pubmed, doi:10.3233/JAD-200374. Full Text

Pages

Polascik, Bryce, et al. “COGNITIVE CONSEQUENCES OF COVID-19 IN OLDER ADULTS WITH COGNITIVE IMPAIRMENT.” American Journal of Geriatric Psychiatry, vol. 29, no. 4, 2021, pp. S75–76.

Devinney, Michael, et al. “The SANDMAN Study: Sleep Apnea, Neuroinflammation, and Cognitive Dysfunction Manifesting After Non-cardiac surgery.” Anesthesia and Analgesia, vol. 130, 2020, pp. 514–15.

Devinney, Michael, et al. “THE SANDMAN STUDY: SLEEP APNEA, NEUROINFLAMMATION, AND COGNITIVE DYSFUNCTION MANIFESTING AFTER NON-CARDIAC SURGERY.” Anesthesia and Analgesia, vol. 128, 2019, pp. 918–918.

Bunning, Thomas, et al. “THE INTUIT STUDY: INVESTIGATING NEUROINFLAMMATION UNDERLYING POSTOPERATIVE NEUROCOGNITIVE DYSFUNCTION AND DELIRIUM IN OLDER ADULTS.” Anesthesia and Analgesia, vol. 128, 2019, pp. 432–432.

Devinney, M. J., et al. “The Association of Obstructive Sleep Apnea Risk with Postoperative Cognitive Decline.” Journal of the American Geriatrics Society, vol. 67, WILEY, 2019, pp. S178–S178.

Heflin, M., et al. “POSH-DREAM: Mobile Point-of-Contact Delirium Risk Assessment & Identification.” Journal of the American Geriatrics Society, vol. 67, WILEY, 2019, pp. S136–S136.

Oyeyemi, D., et al. “Depression, Anxiety and Postoperative Cognition in Older Adults.” Journal of the American Geriatrics Society, vol. 67, WILEY, 2019, pp. S338–S338.

Khan, Babar A., et al. “DECONSTRUCTING DELIRIUM: RETHINKING THE ROLE OF BIOMARKERS AND DIAGNOSTIC ANOMALIES.” The American Journal of Geriatric Psychiatry, vol. 27, no. 3, Elsevier BV, 2019, pp. S38–39. Crossref, doi:10.1016/j.jagp.2019.01.188. Full Text

Berger, M., et al. “Postoperative Changes in CSF AD Markers, Cognition, and fMRI activity.” Journal of the American Geriatrics Society, vol. 66, WILEY, 2018, pp. S5–S5.

Pages