Jeffrey Nicholas Browndyke

Jeffrey Nicholas Browndyke

Associate Professor of Psychiatry and Behavioral Sciences

External Address: 
Durham VA Box 116-A, 508 Fulton St, Durham, NC 27705
Internal Office Address: 
Durham VA Box 116-A, 508 Fulton St, Durham, NC 27710


Dr. Browndyke is an Associate Professor of Behavioral Health & Neurosciences in the Department of Psychiatry & Behavioral Sciences.  He has a secondary appointment as Assistant Professor of Cardiovascular & Thoracic Surgery.

Dr. Browndyke's research interests involve the use of advanced neurocognitive and neuroimaging techniques for perioperative contributions to delirium and later dementia risk, monitoring of late-life neuropathological disease progression, and intervention/treatment outcomes.  His research also involves novel telehealth methods for remote neurocognitive evaluation and implementation of non-invasive neuromodulatory techniques to assist in postoperative recovery and dementia risk reduction.

Dr. Browndyke's clinical expertise is focused upon geriatric neuropsychology with an emphasis in the assessment, diagnosis, and treatment of dementia and related disorders in adults and US veteran patient populations.

Education & Training

  • Psychology Fellowship Program, Psychology, Brown University, Warren Alpert Medical School 2000 - 2003

  • Ph.D., Louisiana State University, Baton Rouge 2001

Browndyke, Jeffrey N., et al. “Phenotypic regional functional imaging patterns during memory encoding in mild cognitive impairment and Alzheimer's disease.Alzheimers Dement, vol. 9, no. 3, May 2013, pp. 284–94. Pubmed, doi:10.1016/j.jalz.2011.12.006. Full Text Open Access Copy

Fontes, Monique T., et al. “Predictors of cognitive recovery after cardiac surgery.Anesth Analg, vol. 116, no. 2, Feb. 2013, pp. 435–42. Pubmed, doi:10.1213/ANE.0b013e318273f37e. Full Text

Blumenthal, James A., et al. “Can lifestyle modification improve neurocognition? Rationale and design of the ENLIGHTEN clinical trial.Contemp Clin Trials, vol. 34, no. 1, Jan. 2013, pp. 60–69. Pubmed, doi:10.1016/j.cct.2012.09.004. Full Text

Giovanello, Kelly S., et al. “Event-related functional magnetic resonance imaging changes during relational retrieval in normal aging and amnestic mild cognitive impairment.J Int Neuropsychol Soc, vol. 18, no. 5, Sept. 2012, pp. 886–97. Pubmed, doi:10.1017/S1355617712000689. Full Text

Wee, Chong-Yaw, et al. “Identification of MCI individuals using structural and functional connectivity networks.Neuroimage, vol. 59, no. 3, Feb. 2012, pp. 2045–56. Pubmed, doi:10.1016/j.neuroimage.2011.10.015. Full Text

Wee, Chong-Yaw, et al. “Resting-state multi-spectrum functional connectivity networks for identification of MCI patients.Plos One, vol. 7, no. 5, 2012, p. e37828. Pubmed, doi:10.1371/journal.pone.0037828. Full Text

Tosun, Duygu, et al. “Spatial patterns of brain amyloid-beta burden and atrophy rate associations in mild cognitive impairment.Brain, vol. 134, no. Pt 4, Apr. 2011, pp. 1077–88. Pubmed, doi:10.1093/brain/awr044. Full Text

Hayden, Kathleen M., et al. “Factor structure of the National Alzheimer's Coordinating Centers uniform dataset neuropsychological battery: an evaluation of invariance between and within groups over time.Alzheimer Dis Assoc Disord, vol. 25, no. 2, Apr. 2011, pp. 128–37. Pubmed, doi:10.1097/WAD.0b013e3181ffa76d. Full Text

Kauwe, John S. K., et al. “Fine mapping of genetic variants in BIN1, CLU, CR1 and PICALM for association with cerebrospinal fluid biomarkers for Alzheimer's disease.Plos One, vol. 6, no. 2, Feb. 2011, p. e15918. Pubmed, doi:10.1371/journal.pone.0015918. Full Text

Wee, Chong-Yaw, et al. “Enriched white matter connectivity networks for accurate identification of MCI patients.Neuroimage, vol. 54, no. 3, Feb. 2011, pp. 1812–22. Pubmed, doi:10.1016/j.neuroimage.2010.10.026. Full Text