Leslie Carol Osborne

Leslie Carol Osborne

Assistant Research Professor of Neurobiology

External Address: 
327 Bryan Research Bldg, 311 Research Drive, Durham, NC 27710
Internal Office Address: 
327M Bryan Research Bldg, 311 Research Drive, Durham, NC 27710


Education & Training

  • Ph.D., University of California at Berkeley 1996

Selected Grants

Cortical Motion Coding and Gaze Control in Natural Vision awarded by National Science Foundation (Principal Investigator). 2018 to 2020

Biological design features that retard visual detection and recognition awarded by (Principal Investigator). 2018 to 2020

Mechanisms of efficient coding of dynamic visual motion signals for pursuit awarded by National Institutes of Health (Principal Investigator). 2014 to 2020

Lombardo, Joseph A., et al. “State dependence of stimulus-induced variability tuning in macaque MT..” Plos Comput Biol, vol. 14, no. 10, Oct. 2018. Pubmed, doi:10.1371/journal.pcbi.1006527. Full Text

Vaidya, Mukta, et al. “Emergent coordination underlying learning to reach to grasp with a brain-machine interface..” J Neurophysiol, vol. 119, no. 4, Apr. 2018, pp. 1291–304. Pubmed, doi:10.1152/jn.00982.2016. Full Text

Mukherjee, Trishna, et al. “Spatiotemporal Filter for Visual Motion Integration from Pursuit Eye Movements in Humans and Monkeys..” J Neurosci, vol. 37, no. 6, Feb. 2017, pp. 1394–412. Pubmed, doi:10.1523/JNEUROSCI.2682-16.2016. Full Text

Liu, Bing, et al. “Efficient sensory cortical coding optimizes pursuit eye movements..” Nat Commun, vol. 7, Sept. 2016. Pubmed, doi:10.1038/ncomms12759. Full Text

Mukherjee, Trishna, et al. “Shared sensory estimates for human motion perception and pursuit eye movements..” J Neurosci, vol. 35, no. 22, June 2015, pp. 8515–30. Pubmed, doi:10.1523/JNEUROSCI.4320-14.2015. Full Text

Osborne, Leslie C. “Computation and physiology of sensory-motor processing in eye movements..” Curr Opin Neurobiol, vol. 21, no. 4, Aug. 2011, pp. 623–28. Pubmed, doi:10.1016/j.conb.2011.05.023. Full Text

Osborne, Leslie C., and Stephen G. Lisberger. “Spatial and temporal integration of visual motion signals for smooth pursuit eye movements in monkeys..” J Neurophysiol, vol. 102, no. 4, Oct. 2009, pp. 2013–25. Pubmed, doi:10.1152/jn.00611.2009. Full Text

Osborne, Leslie C., et al. “The neural basis for combinatorial coding in a cortical population response..” J Neurosci, vol. 28, no. 50, Dec. 2008, pp. 13522–31. Pubmed, doi:10.1523/JNEUROSCI.4390-08.2008. Full Text

Osborne, Leslie C., et al. “Time course of precision in smooth-pursuit eye movements of monkeys..” J Neurosci, vol. 27, no. 11, Mar. 2007, pp. 2987–98. Pubmed, doi:10.1523/JNEUROSCI.5072-06.2007. Full Text

Osborne, Leslie C., et al. “A sensory source for motor variation..” Nature, vol. 437, no. 7057, Sept. 2005, pp. 412–16. Pubmed, doi:10.1038/nature03961. Full Text


Bearden, A., et al. “Laser-feedback microscopy: fundamental principles and application to high-resolution biological imaging.” Proceedings  Annual Meeting, Microscopy Society of America, 1993, pp. 84–85.