Nancy Lee Zucker

Nancy Lee Zucker

Associate Professor in Psychiatry and Behavioral Sciences

External Address: 
905 W. Main Street, Suite 22B Brightleaf Square, Durham, NC 27701
Internal Office Address: 
Box 3454 Med Ctr, Durham, NC 27710


Our laboratory studies individuals who have difficulty detecting, interpreting, and/or using signals from their body and using this information to guide adaptive behavior, particularly in interpersonal contexts. Our primary populations of study are individuals struggling with eating disorders and feeding disorders of childhood: conditions that are sine quo non for dysregulation of basic motivational drives. Several conditions are of particular focus due to the presence of profound deficits in interoception or/and integration of internal arousal: anorexia nervosa, a disorder notable for extreme, determined, rigid, and repetitive behaviors promoting malnourishment and the inability to use signals of interoception and proprioception in the service of goal-directed actions, pediatric binge eating, a model of appetitive dysregulation marked for its early occurrence in the life cycle, and childhood feeding disorders, children who evidence early disturbance in the range of foodstuffs they are willing to sample. Study of children allows us to ask different questions about disorder etiology, maintenance, and course as we can minimize the impact of malnutrition on brain function and perhaps better characterize prior learning history.

Our parallel line of research examines how individuals’ sense others when they have difficulties sensing themselves. Increasing evidence suggests that we understand others via embodied enactments of our own experiences. These findings have profound implications for individuals who have dysfunction in the experience of their bodies as it suggests limited capacities to truly understand others’ experiences. By studying these processes in parallel, we hope to better understand how this interaction between sensing ourselves and others unfolds.

Education & Training

  • Ph.D., Louisiana State University, Baton Rouge 2000

Selected Grants

SCH: INT: Computational Tools for Avoidant/Restrictive Food Intake Disorder awarded by National Science Foundation (Co-Principal Investigator). 2019 to 2022

Maternal obesity, child executive functions and child weight gain awarded by National Institutes of Health (Co Investigator). 2015 to 2021

A Mind Body Approach to ARFID in Young Children: Food and Body Investigators awarded by (Principal Investigator). 2018 to 2021

Feelings and Body Investigators: Interoceptive Exposure for Children with Abdominal Pain awarded by National Institutes of Health (Principal Investigator). 2013 to 2019

NYU-Duke Lifespan Mental Health Assessment Collaborative awarded by New York University (Principal Investigator). 2018

Defining Remission and Recovery in Eating Disorders awarded by University of North Carolina - Chapel Hill (Principal Investigator). 2016 to 2017

Eating Disorders in Type 1 Diabetes: Mechanisms of Comorbidity awarded by National Institutes of Health (Co Investigator). 2011 to 2015

Neural Mechanisms of Social Reward Valuation and Decision Making awarded by National Institutes of Health (Co Investigator). 2009 to 2014

KAN-DO: A Family-Based Intervention to Prevent Childhood Obesity awarded by National Institutes of Health (Co Investigator). 2006 to 2012


Zucker, N., et al. “Loss of control eating in children.” Eating Disorders and Obesity in Children and Adolescents, 2018, pp. 35–38. Scopus, doi:10.1016/B978-0-323-54852-6.00006-9. Full Text

Zucker, N., et al. “Selective eating: Normative developmental phase or clinical condition?The Oxford Handbook of Eating Disorders, 2017, pp. 419–37. Scopus, doi:10.1093/oxfordhb/9780190620998.013.23. Full Text

Sweeney, C., et al. “Family-based treatment for prodromal anorexia nervosa.” Family Therapy for Adolescent Eating and Weight Disorders: New Applications, 2015, pp. 157–76. Scopus, doi:10.4324/9781315882444. Full Text

Sweeney, C., et al. “Family-based treatment for prodromal anorexia nervosa.” Family Therapy for Adolescent Eating and Weight Disorders: New Applications, 2015, pp. 157–76. Scopus, doi:10.4324/9781315882444-17. Full Text

Zucker, N. “Emotional experience and regulation in eating disorders: Theory, evidence, and translational application to family treatment.” Family Therapy for Adolescent Eating and Weight Disorders: New Applications, 2015, pp. 328–58. Scopus, doi:10.4324/9781315882444-23. Full Text

Zucker, N., and C. Harshaw. “Emotion, Attention, and Relationships: A Developmental Model of Self-Regulation in Anorexia Nervosa and Related Disordered Eating Behaviors.” The Oxford Handbook of Child and Adolescent Eating Disorders Developmental Perspectives, 2012. Scopus, doi:10.1093/oxfordhb/9780199744459.013.0005. Full Text

Calland, Alyssa R., et al. “Associations of self-reported eating disorder behaviors and personality in a college-educated sample.Appetite, vol. 151, Aug. 2020, p. 104669. Pubmed, doi:10.1016/j.appet.2020.104669. Full Text

Fuemmeler, Bernard F., et al. “Associations between attention deficit hyperactivity disorder symptoms and eating behaviors in early childhood.Pediatr Obes, vol. 15, no. 7, July 2020, p. e12631. Pubmed, doi:10.1111/ijpo.12631. Full Text

Schuette, Stephanie A., et al. “Do interoceptive accuracy and interoceptive sensibility predict emotion regulation?Psychological Research, June 2020. Epmc, doi:10.1007/s00426-020-01369-2. Full Text

Zucker, Nancy L., and Sheryl O. Hughes. “The Persistence of Picky Eating: Opportunities to Improve Our Strategies and Messaging.Pediatrics, vol. 145, no. 6, June 2020. Epmc, doi:10.1542/peds.2020-0893. Full Text

Zucker, Nancy L., and Cynthia M. Bulik. “On bells, saliva, and abdominal pain or discomfort: Early aversive visceral conditioning and vulnerability for anorexia nervosa.Int J Eat Disord, vol. 53, no. 4, Apr. 2020, pp. 508–12. Pubmed, doi:10.1002/eat.23255. Full Text

Zickgraf, Hana F., et al. “Rigidity and Sensory Sensitivity: Independent Contributions to Selective Eating in Children, Adolescents, and Young Adults.J Clin Child Adolesc Psychol, Mar. 2020, pp. 1–13. Pubmed, doi:10.1080/15374416.2020.1738236. Full Text

Surwit, Richard S., et al. “Erratum. Hostility, race, and glucose metabolism in nondiabetic individuals. Diabetes Care 2002;25:835-839.Diabetes Care, vol. 43, no. 3, Mar. 2020, p. 691. Pubmed, doi:10.2337/dc20-er03. Full Text

Amoroso, C. R., et al. “Disgust Theory Through the Lens of Psychiatric Medicine.” Clinical Psychological Science, vol. 8, no. 1, Jan. 2020, pp. 3–24. Scopus, doi:10.1177/2167702619863769. Full Text

Bardone-Cone, Anna M., et al. “Eating disorder recovery in men: A pilot study.Int J Eat Disord, vol. 52, no. 12, Dec. 2019, pp. 1370–79. Pubmed, doi:10.1002/eat.23153. Full Text

Carpenter, Kimberly L. H., et al. “Sensory Over-Responsivity: An Early Risk Factor for Anxiety and Behavioral Challenges in Young Children.J Abnorm Child Psychol, vol. 47, no. 6, June 2019, pp. 1075–88. Pubmed, doi:10.1007/s10802-018-0502-y. Full Text


Kass, Andrea E., et al. “Secretive eating among youth with overweight or obesity.Appetite, vol. 114, 2017, pp. 275–81. Pubmed, doi:10.1016/j.appet.2017.03.042. Full Text