Nancy Lee Zucker
Associate Professor in Psychiatry and Behavioral Sciences
Our laboratory studies individuals who have difficulty detecting, interpreting, and/or using signals from their body and using this information to guide adaptive behavior. We explore how disruptions in these capacities contribute to psychosomatic disorders such as functional abdominal pain or anorexia nervosa and how the adaptive development of these capacities helps individuals to know themselves, trust themselves, and flourish.
Our primary populations of study are individuals struggling with eating disorders and feeding disorders of childhood: conditions that are sine quo non for dysregulation of basic motivational drives or conditions in which disruption in these processes may be more likely: such as the presence of pediatric pain. Several conditions are of particular focus due to the presence of profound deficits in interoception or/and integration of internal arousal: anorexia nervosa, a disorder notable for extreme, determined, rigid, and repetitive behaviors promoting malnourishment and the inability to use signals of interoception and proprioception in the service of goal-directed actions, Avoidant Restrictive Food Intake Disorder (ARFID), children with "sensory superpowers" who may be hypersensitive to somatic signals and external sensory features; and pediatric functional abdominal pain, children who may become afraid of their bodies' messages due to generalization of fear of pain to innocuous sensations. Study of children allows us to ask different questions about disorder etiology, maintenance, and course as we can minimize the impact of malnutrition on brain function and perhaps better characterize prior learning history. What we most passionate about is using this conceptualization to design and test novel treatments that enable individuals across the lifespan to feel safe in their bodies and to achieve this in a way that is fun.
Our parallel line of research examines how individuals’ sense others when they have difficulties sensing themselves. Increasing evidence suggests that we understand others via embodied enactments of our own experiences. These findings have profound implications for individuals who have dysfunction in the experience of their bodies as it suggests limited capacities to truly understand others’ experiences. By studying these processes in parallel, we hope to better understand how this interaction between sensing ourselves and others unfolds.
Braden, Abby, et al. “Associations between child emotional eating and general parenting style, feeding practices, and parent psychopathology.” Appetite, vol. 80, Sept. 2014, pp. 35–40. Pubmed, doi:10.1016/j.appet.2014.04.017. Full Text
Pisetsky, D. S., et al. “The expression of cytokines and chemokines in the blood of patients with severe weight loss from anorexia nervosa: an exploratory study.” Cytokine, vol. 69, no. 1, Sept. 2014, pp. 110–15. Pubmed, doi:10.1016/j.cyto.2014.05.018. Full Text
Boutelle, Kerri N., et al. “Overeating phenotypes in overweight and obese children.” Appetite, vol. 76, May 2014, pp. 95–100. Pubmed, doi:10.1016/j.appet.2014.01.076. Full Text
Boutelle, Kerri N., et al. “An intervention based on Schachter's externality theory for overweight children: the regulation of cues pilot.” J Pediatr Psychol, vol. 39, no. 4, May 2014, pp. 405–17. Pubmed, doi:10.1093/jpepsy/jst142. Full Text
Madowitz, Jennifer, et al. “Concurrent and convergent validity of the eating in the absence of hunger questionnaire and behavioral paradigm in overweight children.” Int J Eat Disord, vol. 47, no. 3, Apr. 2014, pp. 287–95. Pubmed, doi:10.1002/eat.22213. Full Text
Patel, Sheetal, et al. “Parents of children with eating disorders: developing theory-based health communication messages to promote caregiver well-being.” J Health Commun, vol. 19, no. 5, 2014, pp. 593–608. Pubmed, doi:10.1080/10810730.2013.821559. Full Text
Runfola, Cristin D., et al. “NURTURE: development and pilot testing of a novel parenting intervention for mothers with histories of an eating disorder.” Int J Eat Disord, vol. 47, no. 1, Jan. 2014, pp. 1–12. Pubmed, doi:10.1002/eat.22178. Full Text
Merwin, Rhonda M., et al. “A Pilot Study of an Acceptance-Based Separated Family Treatment for Adolescent Anorexia Nervosa.” Cogn Behav Pract, vol. 20, no. 4, Nov. 2013, pp. 485–500. Pubmed, doi:10.1016/j.cbpra.2012.11.001. Full Text
Østbye, T., et al. “The effect of the home environment on physical activity and dietary intake in preschool children.” Int J Obes (Lond), vol. 37, no. 10, Oct. 2013, pp. 1314–21. Pubmed, doi:10.1038/ijo.2013.76. Full Text Open Access Copy
Zucker, Nancy L., et al. “Subjective experience of sensation in anorexia nervosa.” Behav Res Ther, vol. 51, no. 6, June 2013, pp. 256–65. Pubmed, doi:10.1016/j.brat.2013.01.010. Full Text Open Access Copy