Niccolò Terrando

Niccolò Terrando

Associate Professor in Anesthesiology

External Address: 
3 Genome Ct, Msrbiii Room 6144, Durham, NC 27710


Education & Training

  • Ph.D., Imperial College London (United Kingdom) 2007

Selected Grants

Bioelectronic regulation of CNS lymphatic drainage in delirium and AD. awarded by Alzheimer's Association (Principal Investigator). 2019 to 2022

Neurovascular dysfunction in delirium superimposed on dementia awarded by National Institutes of Health (Principal Investigator). 2017 to 2022

Neuro-inflammation in Postoperative Cognitive Dysfunction: CSF and fMRI Studies awarded by National Institutes of Health (Collaborator). 2017 to 2022

Targeting microbially-derived juvenile protective factors to resolve neuroinflammation and delirium awarded by National Institutes of Health (Principal Investigator). 2019 to 2021

Bioelectronic rescue of cognitive impairment after surgery awarded by National Institutes of Health (Principal Investigator). 2018 to 2021

Ulinastatin and Postoperative Cognitive Dysfunction awarded by Takeda Pharmaceutical Company Limited (Principal Investigator). 2019 to 2020

Organization and Function of Cellular Structure awarded by National Institutes of Health (Mentor). 1975 to 2020

Role of TLR4 in surgery-induced cognitive decline awarded by Takeda Pharmaceutical Company Limited (Principal Investigator). 2016 to 2018


Yang, Ting, et al. “Neuroinflammation after surgery: from mechanisms to therapeutic targets.Nat Immunol, vol. 21, no. 11, Nov. 2020, pp. 1319–26. Pubmed, doi:10.1038/s41590-020-00812-1. Full Text

Miller-Rhodes, Patrick, et al. “This Is Your Brain on (Low) Glucose.Trends Neurosci, Sept. 2020. Pubmed, doi:10.1016/j.tins.2020.09.002. Full Text

Wang, Dian-Shi, et al. “Targeting microglia to mitigate perioperative neurocognitive disorders.Br J Anaesth, vol. 125, no. 3, Sept. 2020, pp. 229–32. Pubmed, doi:10.1016/j.bja.2020.06.027. Full Text

Wang, Ping, et al. “Neurovascular and immune mechanisms that regulate postoperative delirium superimposed on dementia.Alzheimers Dement, vol. 16, no. 5, May 2020, pp. 734–49. Pubmed, doi:10.1002/alz.12064. Full Text

Bassi, Gabriel S., et al. “Anatomical and clinical implications of vagal modulation of the spleen.Neuroscience and Biobehavioral Reviews, vol. 112, May 2020, pp. 363–73. Epmc, doi:10.1016/j.neubiorev.2020.02.011. Full Text

Eckenhoff, Roderic G., et al. “Perioperative Neurocognitive Disorder: State of the Preclinical Science.Anesthesiology, vol. 132, no. 1, Jan. 2020, pp. 55–68. Pubmed, doi:10.1097/ALN.0000000000002956. Full Text

VanDusen, Keith W., et al. “The MARBLE Study Protocol: Modulating ApoE Signaling to Reduce Brain Inflammation, DeLirium, and PostopErative Cognitive Dysfunction.J Alzheimers Dis, vol. 75, no. 4, 2020, pp. 1319–28. Pubmed, doi:10.3233/JAD-191185. Full Text Open Access Copy

Miller-Rhodes, Patrick, et al. “The broad spectrum mixed-lineage kinase 3 inhibitor URMC-099 prevents acute microgliosis and cognitive decline in a mouse model of perioperative neurocognitive disorders.J Neuroinflammation, vol. 16, no. 1, Oct. 2019, p. 193. Pubmed, doi:10.1186/s12974-019-1582-5. Full Text

Terrando, Niccolò, and David S. Warner. “Xenon for traumatic brain injury: a noble step forward and a wet blanket.Br J Anaesth, vol. 123, no. 1, July 2019, pp. 9–11. Pubmed, doi:10.1016/j.bja.2019.04.004. Full Text

Klinger, Rebecca Y., et al. “Intravenous Lidocaine Does Not Improve Neurologic Outcomes after Cardiac Surgery: A Randomized Controlled Trial.Anesthesiology, vol. 130, no. 6, June 2019, pp. 958–70. Epmc, doi:10.1097/aln.0000000000002668. Full Text