Niccolò Terrando

Niccolò Terrando

Associate Professor of Anesthesiology

External Address: 
3 Genome Ct, Msrbiii Room 6144, Durham, NC 27710


Education & Training

  • Ph.D., Imperial College London (United Kingdom) 2007

Selected Grants

Cell and Molecular Biology Training Program awarded by National Institutes of Health (Mentor). 2021 to 2026

Integrated Training in Anesthesiology Research awarded by National Institutes of Health (Mentor). 1996 to 2026

Protective role of Clec7a/dectin-1 in CNS autoimmunity awarded by National Institutes of Health (Collaborator). 2020 to 2025

Bioelectronic regulation of CNS lymphatic drainage in delirium and AD. awarded by Alzheimer's Association (Principal Investigator). 2019 to 2023

Immunoprofiling postoperative delirium during aging and neurodegeneration awarded by University of Rochester Medical Center (Principal Investigator). 2021 to 2023

The Association of Blood-Brain Barrier Breakdown with Sleep Apnea and Postoperative Delirium awarded by National Institutes of Health (Advisor). 2021 to 2023

Neurovascular dysfunction in delirium superimposed on dementia awarded by National Institutes of Health (Principal Investigator). 2017 to 2023

Neuro-inflammation in Postoperative Cognitive Dysfunction: CSF and fMRI Studies awarded by National Institutes of Health (Collaborator). 2017 to 2023

Targeting microbially-derived juvenile protective factors to resolve neuroinflammation and delirium awarded by National Institutes of Health (Principal Investigator). 2019 to 2022


Miller-Rhodes, Patrick, et al. “URMC-099 prophylaxis prevents hippocampal vascular vulnerability and synaptic damage in an orthopedic model of delirium superimposed on dementia.Faseb J, vol. 36, no. 6, June 2022, p. e22343. Pubmed, doi:10.1096/fj.202200184RR. Full Text

Gordon, Marcia N., et al. “Impact of COVID-19 on the Onset and Progression of Alzheimer's Disease and Related Dementias: A Roadmap for Future Research.Alzheimers Dement, vol. 18, no. 5, May 2022, pp. 1038–46. Pubmed, doi:10.1002/alz.12488. Full Text

Zhang, Zhiquan, et al. “Annexin-A1 Tripeptide Attenuates Surgery-Induced Neuroinflammation and Memory Deficits Through Regulation the NLRP3 Inflammasome.Front Immunol, vol. 13, 2022, p. 856254. Pubmed, doi:10.3389/fimmu.2022.856254. Full Text

Velagapudi, R., et al. “Percutaneous vagus nerve stimulation modulates glia activity and rescues acute Aβ deposition in a mouse model of delirium superimposed on dementia.” Alzheimer’S &Amp; Dementia : The Journal of the Alzheimer’S Association, vol. 17, Dec. 2021, p. e056571. Scopus, doi:10.1002/alz.056571. Full Text

Terrando, Niccolò, et al. “Immunomodulatory lipid mediator profiling of cerebrospinal fluid following surgery in older adults.Sci Rep, vol. 11, no. 1, Feb. 2021, p. 3047. Pubmed, doi:10.1038/s41598-021-82606-5. Full Text Open Access Copy

Maurer, Sara V., et al. “Dietary Choline Protects Against Cognitive Decline After Surgery in Mice.Front Cell Neurosci, vol. 15, 2021, p. 671506. Pubmed, doi:10.3389/fncel.2021.671506. Full Text

VanDusen, Keith W., et al. “Cerebrospinal Fluid Proteome Changes in Older Non-Cardiac Surgical Patients with Postoperative Cognitive Dysfunction.J Alzheimers Dis, vol. 80, no. 3, 2021, pp. 1281–97. Pubmed, doi:10.3233/JAD-201544. Full Text Open Access Copy

Miller-Rhodes, Patrick, et al. “This Is Your Brain on (Low) Glucose.Trends Neurosci, vol. 43, no. 12, Dec. 2020, pp. 933–35. Pubmed, doi:10.1016/j.tins.2020.09.002. Full Text

Yang, Ting, et al. “Neuroinflammation after surgery: from mechanisms to therapeutic targets.Nat Immunol, vol. 21, no. 11, Nov. 2020, pp. 1319–26. Pubmed, doi:10.1038/s41590-020-00812-1. Full Text