Nicole Calakos

Nicole Calakos

Professor in Neurology

External Address: 
201E Bryan Res Bldg, Durham, NC 27710
Internal Office Address: 
Duke Box 2900, Durham, NC 27710
Phone: 
919.684.2423

Overview

Education & Training

  • Resident in Neurology, Medicine, University of California, San Francisco, School of Medicine 1997 - 2000

  • Intern in Medicine, Medicine, University of California, San Francisco, School of Medicine 1996 - 1997

  • M.D., Stanford University 1996

  • Ph.D., Stanford University 1995

Calakos, N. “Botulinum toxin: From molecule to clinic.” Handbook of Dystonia, 2006, pp. 343–54.

Sanders, Laurie H., and Nicole Calakos. “Dopamine Metabolism May Have Unexpected Benefits for Mitochondrial Energy Production.Mov Disord, vol. 35, no. 4, Apr. 2020, p. 562. Pubmed, doi:10.1002/mds.28005. Full Text

Lungu, Codrin, et al. “Defining research priorities in dystonia.Neurology, vol. 94, no. 12, Mar. 2020, pp. 526–37. Pubmed, doi:10.1212/WNL.0000000000009140. Full Text

O’Hare, Justin, et al. “Recent Insights into Corticostriatal Circuit Mechanisms underlying Habits: Invited review for Current Opinions in Behavioral Sciences.Current Opinion in Behavioral Sciences, vol. 20, Apr. 2018, pp. 40–46. Epmc, doi:10.1016/j.cobeha.2017.10.001. Full Text

Wang, Xiaoting, et al. “Parvalbumin Interneurons of the Mouse Nucleus Accumbens are Required For Amphetamine-Induced Locomotor Sensitization and Conditioned Place Preference.Neuropsychopharmacology, vol. 43, no. 5, Apr. 2018, pp. 953–63. Pubmed, doi:10.1038/npp.2017.178. Full Text

O’Hare, Justin K., et al. “Striatal fast-spiking interneurons selectively modulate circuit output and are required for habitual behavior.Elife, vol. 6, Sept. 2017. Pubmed, doi:10.7554/eLife.26231. Full Text

Hernandez-Martinez, Ricardo, and Nicole Calakos. “Seq-ing the Circuit Logic of the Basal Ganglia.Trends Neurosci, vol. 40, no. 6, June 2017, pp. 325–27. Pubmed, doi:10.1016/j.tins.2017.04.006. Full Text

Rittiner, Joseph E., et al. “Functional Genomic Analyses of Mendelian and Sporadic Disease Identify Impaired eIF2α Signaling as a Generalizable Mechanism for Dystonia.Neuron, vol. 92, no. 6, Dec. 2016, pp. 1238–51. Pubmed, doi:10.1016/j.neuron.2016.11.012. Full Text

Ade, Kristen K., et al. “Increased Metabotropic Glutamate Receptor 5 Signaling Underlies Obsessive-Compulsive Disorder-like Behavioral and Striatal Circuit Abnormalities in Mice.Biol Psychiatry, vol. 80, no. 7, Oct. 2016, pp. 522–33. Pubmed, doi:10.1016/j.biopsych.2016.04.023. Full Text

Bhagat, Srishti L., et al. “Mouse model of rare TOR1A variant found in sporadic focal dystonia impairs domains affected in DYT1 dystonia patients and animal models.Neurobiol Dis, vol. 93, Sept. 2016, pp. 137–45. Pubmed, doi:10.1016/j.nbd.2016.05.003. Full Text

O’Hare, Justin K., et al. “Pathway-Specific Striatal Substrates for Habitual Behavior.Neuron, vol. 89, no. 3, Feb. 2016, pp. 472–79. Pubmed, doi:10.1016/j.neuron.2015.12.032. Full Text

Pages

Calakos, Nicole. “From Good Habit to Bad: Corticostriatal Synaptic and Circuit Mechanisms in Habit and Compulsion.” Neuropsychopharmacology, vol. 40, NATURE PUBLISHING GROUP, 2015, pp. S38–39.

Jay, C. A., and N. Calakos. “Heroin inhalation and leukoencephalopathy: A case series from California.” Neurology, vol. 52, no. 6, LIPPINCOTT WILLIAMS & WILKINS, 1999, pp. A446–A446.

Calakos, N., et al. “Cortical manifestations of the osmotic myelinolysis syndrome identified by MRI.” Neurology, vol. 52, no. 6, LIPPINCOTT WILLIAMS & WILKINS, 1999, pp. A80–81.

PEVSNER, J., et al. “MOLECULAR MECHANISMS OF SYNAPTIC TRANSMISSION.” Faseb Journal, vol. 9, no. 6, FEDERATION AMER SOC EXP BIOL, 1995, pp. A1457–A1457.

CALAKOS, N., et al. “PROTEIN DOMAINS IMPORTANT FOR TARGETING OF THE SYNAPTIC VESICLE PROTEIN, VAMP.” Journal of Cellular Biochemistry, WILEY-LISS, 1993, pp. 279–279.

BENNETT, M. K., et al. “SYNTAXIN - A SYNAPTIC PROTEIN IMPLICATED IN DOCKING OF SYNAPTIC VESICLES AT PRESYNAPTIC ACTIVE ZONES.” Molecular Biology of the Cell, vol. 3, AMER SOC CELL BIOLOGY, 1992, pp. A3–A3.