Nicole Calakos

Nicole Calakos

Lincoln Financial Group Distinguished Professor of Neurobiology

External Address: 
201E Bryan Res Bldg, Durham, NC 27710
Internal Office Address: 
Duke Box 2900, Durham, NC 27710
Phone: 
919.684.2423

Overview

Education & Training

  • Resident in Neurology, Medicine, University of California San Francisco, School of Medicine 1997 - 2000

  • Intern in Medicine, Medicine, University of California San Francisco, School of Medicine 1996 - 1997

  • M.D., Stanford University 1996

  • Ph.D., Stanford University 1995

Calakos, N. “Botulinum toxin: From molecule to clinic.” Handbook of Dystonia, 2006, pp. 343–54.

Caffall, Zachary F., et al. “The HIV protease inhibitor, ritonavir, corrects diverse brain phenotypes across development in mouse model of DYT-TOR1A dystonia.Sci Transl Med, vol. 13, no. 607, Aug. 2021. Pubmed, doi:10.1126/scitranslmed.abd3904. Full Text

Shroff, Kunal, et al. “DYT-TOR1A subcellular proteomics reveals selective vulnerability of the nuclear proteome to cell stress.Neurobiol Dis, vol. 158, Aug. 2021, p. 105464. Pubmed, doi:10.1016/j.nbd.2021.105464. Full Text

Helseth, Ashley R., et al. “Cholinergic neurons constitutively engage the ISR for dopamine modulation and skill learning in mice.Science, vol. 372, no. 6540, Apr. 2021. Pubmed, doi:10.1126/science.abe1931. Full Text

Rahimpour, Shervin, et al. “Treatment of diaphragmatic dystonia with pallidal deep brain stimulation.Bmj Case Rep, vol. 14, no. 3, Mar. 2021. Pubmed, doi:10.1136/bcr-2020-240510. Full Text

Isaacson, Stuart H., et al. “Prospective Home-use Study on Non-invasive Neuromodulation Therapy for Essential Tremor.Tremor and Other Hyperkinetic Movements (New York, N.Y.), vol. 10, Aug. 2020, p. 29. Epmc, doi:10.5334/tohm.59. Full Text

Sanders, Laurie H., and Nicole Calakos. “Dopamine Metabolism May Have Unexpected Benefits for Mitochondrial Energy Production.Mov Disord, vol. 35, no. 4, Apr. 2020, p. 562. Pubmed, doi:10.1002/mds.28005. Full Text

Lungu, Codrin, et al. “Defining research priorities in dystonia.Neurology, vol. 94, no. 12, Mar. 2020, pp. 526–37. Pubmed, doi:10.1212/WNL.0000000000009140. Full Text

O’Hare, Justin, et al. “Recent Insights into Corticostriatal Circuit Mechanisms underlying Habits: Invited review for Current Opinions in Behavioral Sciences.Curr Opin Behav Sci, vol. 20, Apr. 2018, pp. 40–46. Pubmed, doi:10.1016/j.cobeha.2017.10.001. Full Text

Wang, Xiaoting, et al. “Parvalbumin Interneurons of the Mouse Nucleus Accumbens are Required For Amphetamine-Induced Locomotor Sensitization and Conditioned Place Preference.Neuropsychopharmacology, vol. 43, no. 5, Apr. 2018, pp. 953–63. Pubmed, doi:10.1038/npp.2017.178. Full Text

O’Hare, Justin K., et al. “Striatal fast-spiking interneurons selectively modulate circuit output and are required for habitual behavior.Elife, vol. 6, Sept. 2017. Pubmed, doi:10.7554/eLife.26231. Full Text

Pages

Calakos, Nicole. “From Good Habit to Bad: Corticostriatal Synaptic and Circuit Mechanisms in Habit and Compulsion.” Neuropsychopharmacology, vol. 40, NATURE PUBLISHING GROUP, 2015, pp. S38–39.

Jay, C. A., and N. Calakos. “Heroin inhalation and leukoencephalopathy: A case series from California.” Neurology, vol. 52, no. 6, LIPPINCOTT WILLIAMS & WILKINS, 1999, pp. A446–A446.

Calakos, N., et al. “Cortical manifestations of the osmotic myelinolysis syndrome identified by MRI.” Neurology, vol. 52, no. 6, LIPPINCOTT WILLIAMS & WILKINS, 1999, pp. A80–81.

PEVSNER, J., et al. “MOLECULAR MECHANISMS OF SYNAPTIC TRANSMISSION.” Faseb Journal, vol. 9, no. 6, FEDERATION AMER SOC EXP BIOL, 1995, pp. A1457–A1457.

CALAKOS, N., et al. “PROTEIN DOMAINS IMPORTANT FOR TARGETING OF THE SYNAPTIC VESICLE PROTEIN, VAMP.” Journal of Cellular Biochemistry, WILEY-LISS, 1993, pp. 279–279.

BENNETT, M. K., et al. “SYNTAXIN - A SYNAPTIC PROTEIN IMPLICATED IN DOCKING OF SYNAPTIC VESICLES AT PRESYNAPTIC ACTIVE ZONES.” Molecular Biology of the Cell, vol. 3, AMER SOC CELL BIOLOGY, 1992, pp. A3–A3.