Nicole Calakos

Nicole Calakos

Lincoln Financial Group Distinguished Professor of Neurobiology

External Address: 
311 Bryan Res Drive, Durham, NC 27710
Internal Office Address: 
Duke Box 2900, Durham, NC 27710


Education & Training

  • Resident in Neurology, Medicine, University of California San Francisco, School of Medicine 1997 - 2000

  • Intern in Medicine, Medicine, University of California San Francisco, School of Medicine 1996 - 1997

  • M.D., Stanford University 1996

  • Ph.D., Stanford University 1995

O’Hare, Justin K., et al. “Striatal fast-spiking interneurons selectively modulate circuit output and are required for habitual behavior.Elife, vol. 6, Sept. 2017. Pubmed, doi:10.7554/eLife.26231. Full Text

Hernandez-Martinez, Ricardo, and Nicole Calakos. “Seq-ing the Circuit Logic of the Basal Ganglia.Trends Neurosci, vol. 40, no. 6, June 2017, pp. 325–27. Pubmed, doi:10.1016/j.tins.2017.04.006. Full Text

Rittiner, Joseph E., et al. “Functional Genomic Analyses of Mendelian and Sporadic Disease Identify Impaired eIF2α Signaling as a Generalizable Mechanism for Dystonia.Neuron, vol. 92, no. 6, Dec. 2016, pp. 1238–51. Pubmed, doi:10.1016/j.neuron.2016.11.012. Full Text

Ade, Kristen K., et al. “Increased Metabotropic Glutamate Receptor 5 Signaling Underlies Obsessive-Compulsive Disorder-like Behavioral and Striatal Circuit Abnormalities in Mice.Biol Psychiatry, vol. 80, no. 7, Oct. 2016, pp. 522–33. Pubmed, doi:10.1016/j.biopsych.2016.04.023. Full Text

Bhagat, Srishti L., et al. “Mouse model of rare TOR1A variant found in sporadic focal dystonia impairs domains affected in DYT1 dystonia patients and animal models.Neurobiol Dis, vol. 93, Sept. 2016, pp. 137–45. Pubmed, doi:10.1016/j.nbd.2016.05.003. Full Text

O’Hare, Justin K., et al. “Pathway-Specific Striatal Substrates for Habitual Behavior.Neuron, vol. 89, no. 3, Feb. 2016, pp. 472–79. Pubmed, doi:10.1016/j.neuron.2015.12.032. Full Text

Rossi, Mark A., et al. “Spotlight on movement disorders: What optogenetics has to offer.Mov Disord, vol. 30, no. 5, Apr. 2015, pp. 624–31. Pubmed, doi:10.1002/mds.26184. Full Text

Bohórquez, Diego V., et al. “Neuroepithelial circuit formed by innervation of sensory enteroendocrine cells.J Clin Invest, vol. 125, no. 2, Feb. 2015, pp. 782–86. Pubmed, doi:10.1172/JCI78361. Full Text Open Access Copy

Risher, W. Christopher, et al. “Astrocytes refine cortical connectivity at dendritic spines.Elife, vol. 3, Dec. 2014. Pubmed, doi:10.7554/eLife.04047. Full Text Open Access Copy

Wan, Yehong, et al. “Circuit-selective striatal synaptic dysfunction in the Sapap3 knockout mouse model of obsessive-compulsive disorder.Biol Psychiatry, vol. 75, no. 8, Apr. 2014, pp. 623–30. Pubmed, doi:10.1016/j.biopsych.2013.01.008. Full Text