Rajendra A. Morey

Rajendra A. Morey

Associate Professor of Psychiatry and Behavioral Sciences

External Address: 
Brain Imaging Analy Ctr, Hock Plaza, Room 5158, Durham, NC 27710
Internal Office Address: 
Box 3918 Med Ctr, Durham, NC 27710
Phone: 
919.681.4994

Overview

Research in my lab is focused on brain changes associated with posttraumatic stress disorder (PTSD), traumatic brain injury (TBI), and other neuropsychiatric disorders. We apply several advanced methods for understanding brain function including functional MRI, structural MRI, diffusion tensor imaging, and genetic effects.

Education & Training

  • M.D., Drexel University 1997

  • M.S., Case Western Reserve University 1992

  • B.S., Case Western Reserve University 1985

Selected Grants

Neurobiologically-Based Subtyping of Multi-Cohort Samples with MDD and PTSD Symptoms awarded by National Institutes of Health (Principal Investigator). 2022 to 2026

Advancing Secondary Data Analysis: the ENIGMA Brain Injury Data Harmonization Initiative awarded by Pennsylvania State University (Principal Investigator). 2020 to 2022

Trauma and Genomics Modulate Brain Structure across Common Psychiatric Disorders awarded by National Institutes of Health (Principal Investigator). 2017 to 2022

IPA - Ryan Wagner awarded by Durham Veterans Affairs Medical Center (Principal Investigator). 2021 to 2022

A High-Performance 3T MRI for Brain Imaging awarded by National Institutes of Health (Major User). 2021 to 2022

ENIGMA-SD: Understanding Sex Differences in Global Mental Health through ENIGMA awarded by University of Southern California (Principal Investigator). 2018 to 2022

IPA - Delin Sun awarded by Durham Veterans Affairs Medical Center (Principal Investigator). 2019 to 2021

RAM Replay Clinical Outcomes for TBI/Suicidality Option awarded by Teledyne Scientific & Imaging, LLC (Principal Investigator). 2019 to 2021

Pages

Junglen, A. G., et al. “Current progress and future direction in the genetics of PTSD: Focus on the development and contributions of the PGC-PTSD working group.” Personalized Psychiatry, 2019, pp. 285–96. Scopus, doi:10.1016/B978-0-12-813176-3.00023-7. Full Text

Bouchard, Heather C., et al. “Age-dependent white matter disruptions after military traumatic brain injury: Multivariate analysis results from ENIGMA brain injury.Hum Brain Mapp, vol. 43, no. 8, June 2022, pp. 2653–67. Pubmed, doi:10.1002/hbm.25811. Full Text

Bountress, Kaitlin E., et al. “Alcohol use and alcohol use disorder differ in their genetic relationships with PTSD: A genomic structural equation modelling approach.Drug Alcohol Depend, vol. 234, May 2022, p. 109430. Pubmed, doi:10.1016/j.drugalcdep.2022.109430. Full Text

Maihofer, Adam X., et al. “Enhancing Discovery of Genetic Variants for Posttraumatic Stress Disorder Through Integration of Quantitative Phenotypes and Trauma Exposure Information.Biol Psychiatry, vol. 91, no. 7, Apr. 2022, pp. 626–36. Pubmed, doi:10.1016/j.biopsych.2021.09.020. Full Text

Waller, Lea, et al. “ENIGMA HALFpipe: Interactive, reproducible, and efficient analysis for resting-state and task-based fMRI data.Hum Brain Mapp, Mar. 2022. Pubmed, doi:10.1002/hbm.25829. Full Text

Sun, Delin, et al. “Remodeling of the Cortical Structural Connectome in Posttraumatic Stress Disorder: Results from the ENIGMA-PGC PTSD Consortium.Biol Psychiatry Cogn Neurosci Neuroimaging, Mar. 2022. Pubmed, doi:10.1016/j.bpsc.2022.02.008. Full Text

Monsour, Molly, et al. “The impact of climate change on the prevalence of mental illness symptoms.J Affect Disord, vol. 300, Mar. 2022, pp. 430–40. Pubmed, doi:10.1016/j.jad.2021.12.124. Full Text

Kochunov, Peter, et al. “ENIGMA-DTI: Translating reproducible white matter deficits into personalized vulnerability metrics in cross-diagnostic psychiatric research.Hum Brain Mapp, vol. 43, no. 1, Jan. 2022, pp. 194–206. Pubmed, doi:10.1002/hbm.24998. Full Text

Clausen, Ashley N., et al. “Assessment of brain age in posttraumatic stress disorder: Findings from the ENIGMA PTSD and brain age working groups.Brain Behav, vol. 12, no. 1, Jan. 2022, p. e2413. Pubmed, doi:10.1002/brb3.2413. Full Text

Zheng, Yuanchao, et al. “Trauma and posttraumatic stress disorder modulate polygenic predictors of hippocampal and amygdala volume.Transl Psychiatry, vol. 11, no. 1, Dec. 2021, p. 637. Pubmed, doi:10.1038/s41398-021-01707-x. Full Text

Pages

O’Leary, B., et al. “Classification of PTSD and Non-PTSD Using Cortical Structural Measures in Machine Learning Analyses—Preliminary Study of ENIGMA-Psychiatric Genomics Consortium PTSD Workgroup.” Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), vol. 12241 LNAI, 2020, pp. 118–27. Scopus, doi:10.1007/978-3-030-59277-6_11. Full Text

Salminen, Lauren, et al. “108. Hippocampal Subfield Volumes Relate to Unique Phenotypes of PTSD: International Analysis by the PGC-ENIGMA PTSD Working Group.” Biological Psychiatry, vol. 85, no. 10, Elsevier BV, 2019, pp. S45–S45. Crossref, doi:10.1016/j.biopsych.2019.03.122. Full Text

Dennis, E. L., et al. “ENIGMA military brain injury: A coordinated meta-analysis of diffusion MRI from multiple cohorts.” Proceedings  International Symposium on Biomedical Imaging, vol. 2018-April, 2018, pp. 1386–89. Scopus, doi:10.1109/ISBI.2018.8363830. Full Text

Morey, Rajendra A., et al. “Genome-Wide Association of Neuroimaging Phenotypes in PTSD at Multiple Sites.” Biological Psychiatry, vol. 79, no. 9, ELSEVIER SCIENCE INC, 2016, pp. 165S-165S.

Morey, Rajendra A., et al. “Assessment of Myelin Compromise in Mild Traumatic Brain Injury with Quantitative Susceptibility Mapping.” Biological Psychiatry, vol. 77, no. 9, ELSEVIER SCIENCE INC, 2015, pp. 40S-40S.

Morey, Rajendra A. “Vulnerability or Consequence: Amygdala Volume Changes with PTSD in a Large Case-Controlled Veteran Group.” Biological Psychiatry, vol. 73, no. 9, ELSEVIER SCIENCE INC, 2013, pp. 124S-124S.

Morey, Rajendra A., et al. “Diffusion Tensor Imaging of OEF/OIF Veterans with and without Exposure to Primary Blast Forces.” Biological Psychiatry, vol. 73, no. 9, ELSEVIER SCIENCE INC, 2013, pp. 93S-93S.

Morey, Rajendra A., et al. “Network Analysis of Intrinsic Functional Organization of the Brain in Mild Traumatic Brain Injury.” Biological Psychiatry, vol. 73, no. 9, ELSEVIER SCIENCE INC, 2013, pp. 198S-198S.

Brown, Vanessa M., et al. “Resting State Connectivity Between Amygdalar Subregions and the Prefrontal Cortex is Disrupted in PTSD.” Biological Psychiatry, vol. 71, no. 8, ELSEVIER SCIENCE INC, 2012, pp. 307S-307S.

Morey, Rajendra A., et al. “Clinical Predictors of White Matter Disruption in Chronic Mild Traumatic Brain Injury among Post-9/11 Veterans.” Biological Psychiatry, vol. 69, no. 9, ELSEVIER SCIENCE INC, 2011, pp. 255S-256S.

Pages