Rajendra A. Morey

Rajendra A. Morey

Associate Professor of Psychiatry and Behavioral Sciences

External Address: 
Brain Imaging Analy Ctr, Hock Plaza, Room 5158, Durham, NC 27710
Internal Office Address: 
Box 3918 Med Ctr, Durham, NC 27710
Phone: 
919.681.4994

Overview

Research in my lab is focused on brain changes associated with posttraumatic stress disorder (PTSD), traumatic brain injury (TBI), and other neuropsychiatric disorders. We apply several advanced methods for understanding brain function including functional MRI, structural MRI, diffusion tensor imaging, and genetic effects.

Education & Training

  • M.D., Drexel University 1997

  • M.S., Case Western Reserve University 1992

  • B.S., Case Western Reserve University 1985

Selected Grants

Trauma and Genomics Modulate Brain Structure across Common Psychiatric Disorders awarded by National Institutes of Health (Principal Investigator). 2017 to 2022

IPA - Ryan Wagner awarded by Durham Veterans Affairs Medical Center (Principal Investigator). 2021 to 2022

A High-Performance 3T MRI for Brain Imaging awarded by National Institutes of Health (Major User). 2021 to 2022

ENIGMA-SD: Understanding Sex Differences in Global Mental Health through ENIGMA awarded by University of Southern California (Principal Investigator). 2018 to 2022

Advancing Secondary Data Analysis: the ENIGMA Brain Injury Data Harmonization Initiative awarded by Pennsylvania State University (Principal Investigator). 2020 to 2021

IPA - Delin Sun awarded by Durham Veterans Affairs Medical Center (Principal Investigator). 2019 to 2021

IPA - Ryan Wagner awarded by Durham Veterans Affairs Medical Center (Principal Investigator). 2019 to 2021

RAM Replay Clinical Outcomes for TBI/Suicidality Option awarded by Teledyne Scientific & Imaging, LLC (Principal Investigator). 2019 to 2021

IPA - Emily Clarke awarded by Durham Veterans Affairs Medical Center (Principal Investigator). 2020 to 2021

Pages

Junglen, A. G., et al. “Current progress and future direction in the genetics of PTSD: Focus on the development and contributions of the PGC-PTSD working group.” Personalized Psychiatry, 2019, pp. 285–96. Scopus, doi:10.1016/B978-0-12-813176-3.00023-7. Full Text

Smith, Alicia K., et al. “Epigenome-wide meta-analysis of PTSD across 10 military and civilian cohorts identifies methylation changes in AHRR.Nat Commun, vol. 11, no. 1, Nov. 2020, p. 5965. Pubmed, doi:10.1038/s41467-020-19615-x. Full Text

Morey, Rajendra A., et al. “Genetic predictors of hippocampal subfield volume in PTSD cases and trauma-exposed controls.European Journal of Psychotraumatology, vol. 11, no. 1, July 2020, p. 1785994. Epmc, doi:10.1080/20008198.2020.1785994. Full Text

Faul, Leonard, et al. “Proximal threats promote enhanced acquisition and persistence of reactive fear-learning circuits.Proc Natl Acad Sci U S A, vol. 117, no. 28, July 2020, pp. 16678–89. Pubmed, doi:10.1073/pnas.2004258117. Full Text

Morey, Rajendra A., et al. “Neural correlates of conceptual-level fear generalization in posttraumatic stress disorder.Neuropsychopharmacology, vol. 45, no. 8, July 2020, pp. 1380–89. Pubmed, doi:10.1038/s41386-020-0661-8. Full Text

Kinzel, Philipp, et al. “Serum Neurosteroid Levels Are Associated With Cortical Thickness in Individuals Diagnosed With Posttraumatic Stress Disorder and History of Mild Traumatic Brain Injury.Clin Eeg Neurosci, vol. 51, no. 4, July 2020, pp. 285–99. Pubmed, doi:10.1177/1550059420909676. Full Text

Koch, Saskia B. J., et al. “The role of the dentate gyrus in stress-related disorders.Mol Psychiatry, vol. 25, no. 7, July 2020, pp. 1361–63. Pubmed, doi:10.1038/s41380-019-0572-4. Full Text

Grasby, Katrina L., et al. “The genetic architecture of the human cerebral cortex.Science, vol. 367, no. 6484, Mar. 2020. Pubmed, doi:10.1126/science.aay6690. Full Text Open Access Copy

Pages

O’Leary, B., et al. “Classification of PTSD and Non-PTSD Using Cortical Structural Measures in Machine Learning Analyses—Preliminary Study of ENIGMA-Psychiatric Genomics Consortium PTSD Workgroup.” Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), vol. 12241 LNAI, 2020, pp. 118–27. Scopus, doi:10.1007/978-3-030-59277-6_11. Full Text

Salminen, Lauren, et al. “108. Hippocampal Subfield Volumes Relate to Unique Phenotypes of PTSD: International Analysis by the PGC-ENIGMA PTSD Working Group.” Biological Psychiatry, vol. 85, no. 10, Elsevier BV, 2019, pp. S45–S45. Crossref, doi:10.1016/j.biopsych.2019.03.122. Full Text

Dennis, E. L., et al. “ENIGMA military brain injury: A coordinated meta-analysis of diffusion MRI from multiple cohorts.” Proceedings  International Symposium on Biomedical Imaging, vol. 2018-April, 2018, pp. 1386–89. Scopus, doi:10.1109/ISBI.2018.8363830. Full Text

Morey, Rajendra A., et al. “Genome-Wide Association of Neuroimaging Phenotypes in PTSD at Multiple Sites.” Biological Psychiatry, vol. 79, no. 9, ELSEVIER SCIENCE INC, 2016, pp. 165S-165S.

Morey, Rajendra A., et al. “Assessment of Myelin Compromise in Mild Traumatic Brain Injury with Quantitative Susceptibility Mapping.” Biological Psychiatry, vol. 77, no. 9, ELSEVIER SCIENCE INC, 2015, pp. 40S-40S.

Morey, Rajendra A., et al. “Network Analysis of Intrinsic Functional Organization of the Brain in Mild Traumatic Brain Injury.” Biological Psychiatry, vol. 73, no. 9, ELSEVIER SCIENCE INC, 2013, pp. 198S-198S.

Morey, Rajendra A. “Vulnerability or Consequence: Amygdala Volume Changes with PTSD in a Large Case-Controlled Veteran Group.” Biological Psychiatry, vol. 73, no. 9, ELSEVIER SCIENCE INC, 2013, pp. 124S-124S.

Morey, Rajendra A., et al. “Diffusion Tensor Imaging of OEF/OIF Veterans with and without Exposure to Primary Blast Forces.” Biological Psychiatry, vol. 73, no. 9, ELSEVIER SCIENCE INC, 2013, pp. 93S-93S.

Brown, Vanessa M., et al. “Resting State Connectivity Between Amygdalar Subregions and the Prefrontal Cortex is Disrupted in PTSD.” Biological Psychiatry, vol. 71, no. 8, ELSEVIER SCIENCE INC, 2012, pp. 307S-307S.

Morey, Rajendra A., et al. “Clinical Predictors of White Matter Disruption in Chronic Mild Traumatic Brain Injury among Post-9/11 Veterans.” Biological Psychiatry, vol. 69, no. 9, ELSEVIER SCIENCE INC, 2011, pp. 255S-256S.

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