Shivanand Lad

Shivanand Lad

Professor of Neurosurgery

External Address: 
200 Trent Drive, Blue Zone, Su, Durham, NC 27710
Internal Office Address: 
DUMC 3807, Durham, NC 27710


Dr. Nandan Lad is a neurosurgeon, scientist, and entrepreneur and an Associate Professor at Duke University Medical Center with a focus in Neuromodulation and Neurorestoration.  He is Director of the Duke NeuroInnovations Program, a systematic approach to medical device innovation to large unmet clinical needs.

He completed his MD and PhD in Biochemistry at Chicago Medical School and his neurosurgical residency training at Stanford with fellowships in Surgical Innovation and Functional Neurosurgery.  

Neuromodulation; Neurorestoration; Bioengineering; Medical Device Design; Clinical Trials; Data Science; Health Outcomes.

Education & Training

  • Neurosurgery Resident, Stanford University 2005 - 2011

  • Sterotactic & Functional Neurosurgery Fellow, Stanford University 2008 - 2009

  • Biodesign Innovation Fellow, Stanford University 2007 - 2008

  • General Surgery Internship, Stanford University 2004 - 2005

  • M.D., Rosalind Franklin University of Medicine and Science 2004

  • Ph.D., Rosalind Franklin University of Medicine and Science 2004

Selected Grants

NINDS Research Education Programs for Residents and Fellows in Neurosurgery awarded by National Institutes of Health (Mentor). 2009 to 2025

NEVRO NSRBP awarded by Nevro Corp (Principal Investigator). 2018 to 2023

ReActiv8 Implantable Neuro-stimulation system for Chronic Low Back Pain awarded by Mainstay Medical Ltd. (Principal Investigator). 2017 to 2021

Nevro HF10 Outcomes Analysis awarded by Nevro Corp (Principal Investigator). 2020 to 2021

Validation of Novel Therapeutic Approach for Leptomeningeal Metastases awarded by Minnetronix, Inc (Principal Investigator). 2016 to 2021


Rahimpour, S., and S. P. Lad. “Traumatic brain injury and potential for neuromodulation.” Translational Research in Traumatic Brain Injury, 2016, pp. 353–63.

Adil, Syed M., et al. “Impact of Spinal Cord Stimulation on Opioid Dose Reduction: A Nationwide Analysis.Neurosurgery, vol. 88, no. 1, Dec. 2020, pp. 193–201. Pubmed, doi:10.1093/neuros/nyaa353. Full Text

Krucoff, Max O., et al. “Spinal cord stimulation and rehabilitation in an individual with chronic complete L1 paraplegia due to a conus medullaris injury: motor and functional outcomes at 18 months.Spinal Cord Ser Cases, vol. 6, no. 1, Oct. 2020, p. 96. Pubmed, doi:10.1038/s41394-020-00345-7. Full Text

Spears, Charis A., et al. “Health Care Resource Utilization and Management of Chronic, Refractory Low Back Pain in the United States.Spine (Phila Pa 1976), vol. 45, no. 20, Oct. 2020, pp. E1333–41. Pubmed, doi:10.1097/BRS.0000000000003572. Full Text

Patel, Naresh, et al. “High-Frequency Spinal Cord Stimulation at 10 kHz for the Treatment of Nonsurgical Refractory Back Pain: Design of a Pragmatic, Multicenter, Randomized Controlled Trial.Pain Practice : The Official Journal of World Institute of Pain, Aug. 2020. Epmc, doi:10.1111/papr.12945. Full Text

Cho, James, et al. “Enhancing Reality: A Systematic Review of Augmented Reality in Neuronavigation and Education.World Neurosurg, vol. 139, July 2020, pp. 186–95. Pubmed, doi:10.1016/j.wneu.2020.04.043. Full Text

Williamson, Theresa, et al. “Withdrawal of Life-Supporting Treatment in Severe Traumatic Brain Injury.Jama Surg, June 2020. Pubmed, doi:10.1001/jamasurg.2020.1790. Full Text

Khani, Mohammadreza, et al. “In vitro and numerical simulation of blood removal from cerebrospinal fluid: comparison of lumbar drain to Neurapheresis therapy.Fluids Barriers Cns, vol. 17, no. 1, Mar. 2020, p. 23. Pubmed, doi:10.1186/s12987-020-00185-5. Full Text

Kiyani, Musa, et al. “The longitudinal health economic impact of viral encephalitis in the United States.J Med Microbiol, vol. 69, no. 2, Feb. 2020, pp. 270–79. Pubmed, doi:10.1099/jmm.0.001153. Full Text

Elsamadicy, Aladine A., et al. “Prevalence and Cost Analysis of Chronic Pain After Hernia Repair: A Potential Alternative Approach With Neurostimulation.Neuromodulation : Journal of the International Neuromodulation Society, vol. 22, no. 8, Dec. 2019, pp. 960–69. Epmc, doi:10.1111/ner.12871. Full Text

Adil, Syed M., et al. “Healthcare Economics of Hydrocephalus After Aneurysmal Subarachnoid Hemorrhage in the United States.Transl Stroke Res, vol. 10, no. 6, Dec. 2019, pp. 650–63. Pubmed, doi:10.1007/s12975-019-00697-9. Full Text



Elsamadicy, Aladine Abdalla, et al. “Neurosurgery medical profession liability claims in the United States.” Journal of Neurosurgery, vol. 128, no. 4, AMER ASSOC NEUROLOGICAL SURGEONS, 2018, pp. 43–43.

Farber, Samuel Harrison, et al. “Modeling Healthcare Expenditures associated with Implantable Neurostimulation for Headache Disorders.” Journal of Neurosurgery, vol. 124, no. 4, AMER ASSOC NEUROLOGICAL SURGEONS, 2016, pp. A1165–A1165.

Petraglia, Frank William, et al. “Longer Delays from Pain Diagnosis to Spinal Cord Stimulation Result in Higher Post-Implant Healthcare Utilization.” Journal of Neurosurgery, vol. 123, no. 2, AMER ASSOC NEUROLOGICAL SURGEONS, 2015, pp. A511–A511.

Patel, Vipul Vikrambhai, et al. “Impact of Tailoring Spinal Cord Stimulation Therapy on Clinical Outcomes.” Journal of Neurosurgery, vol. 123, no. 2, AMER ASSOC NEUROLOGICAL SURGEONS, 2015, pp. A516–A516.

Lad, Shivanand P., et al. “Neurostimulation for the Treatment of Headache Disorders: A Large, Retrospective Cohort Analysis.” Journal of Neurosurgery, vol. 122, no. 6, AMER ASSOC NEUROLOGICAL SURGEONS, 2015, pp. A1572–A1572.

Bagley, Jacob, et al. “Predictors And Implications Of Facial Nerve Dysfunction After Acoustic Neuroma Resection: A National Study.” Journal of Neurosurgery, vol. 119, no. 2, AMER ASSOC NEUROLOGICAL SURGEONS, 2013, pp. A563–64.

Babu, Ranjith, et al. “Treatment Of Intraspinal Abscess: Comparison Of Outcomes Following Surgical And Conservative Management.” Journal of Neurosurgery, vol. 119, no. 2, AMER ASSOC NEUROLOGICAL SURGEONS, 2013, pp. A575–A575.

Hazzard, Matthew Aaron, et al. “Comparison Of Management Options For Vertebral Compression Fractures And Impact On US Healthcare Resource Utilization.” Journal of Neurosurgery, vol. 119, no. 2, AMER ASSOC NEUROLOGICAL SURGEONS, 2013, pp. A585–86.

Choi, Jonathan, et al. “157 Utilization of Spinal Cord Stimulation in Patients with Failed Back Surgery Syndrome.” Neurosurgery, vol. 71, no. 2, Oxford University Press (OUP), 2012, pp. E562–63. Crossref, doi:10.1227/01.neu.0000417747.62665.b7. Full Text