Stephen Lisberger

Stephen Lisberger

George Barth Geller Professor for Research in Neurobiology

External Address: 
Bryan Research Building, 311 Research Drive Room 327D, Durham, NC 27710
Internal Office Address: 
Box 3209, Durham, NC 27710
Phone: 
919.681.7088

Overview

We investigate how the brain learns motor skills, and how we use what we see to guide how we move. Our approaches involve studies of eye movements using behavior, neural recordings, and computational analysis. Our work is done on behaving non-human primates. 

Education & Training

  • Ph.D., University of Washington 1976

Selected Grants

Neurobiology Training Program awarded by National Institutes of Health (Mentor). 2019 to 2024

Canonical computations for motor learning by the cerebellar cortex micro-circuit awarded by National Institutes of Health (Principal Investigator). 2019 to 2024

Medical Scientist Training Program awarded by National Institutes of Health (Mentor). 1997 to 2022

Neural Control of Eye Movement awarded by National Institutes of Health (Principal Investigator). 2017 to 2022

Visual-motor integration in smooth pursuit eye movements awarded by National Institutes of Health (Principal Investigator). 2017 to 2021

Neural Basis for Cerebellar Motor Learning awarded by National Institutes of Health (Principal Investigator). 2016 to 2020

The structure and significance of correlated activity among retinal ganglion cells awarded by National Institutes of Health (Co-Sponsor). 2018 to 2020

The structure and significance of correlated activity among retinal ganglion cells awarded by National Institutes of Health (Co-Sponsor). 2018 to 2020

Bioinformatics and Computational Biology Training Program awarded by National Institutes of Health (Mentor). 2005 to 2020

Re-examining the role of cerebellar climbing fibers in motor learning awarded by National Institutes of Health (Co-Sponsor). 2017 to 2019

Pages

Hall, Nathan J., et al. “Multiple components in direction learning in smooth pursuit eye movements of monkeys..” J Neurophysiol, vol. 120, no. 4, Oct. 2018, pp. 2020–35. Pubmed, doi:10.1152/jn.00261.2018. Full Text

Darlington, Timothy R., et al. “Neural implementation of Bayesian inference in a sensorimotor behavior..” Nat Neurosci, vol. 21, no. 10, Oct. 2018, pp. 1442–51. Pubmed, doi:10.1038/s41593-018-0233-y. Full Text

Raghavan, Ramanujan T., and Stephen G. Lisberger. “Responses of Purkinje cells in the oculomotor vermis of monkeys during smooth pursuit eye movements and saccades: comparison with floccular complex..” J Neurophysiol, vol. 118, no. 2, Aug. 2017, pp. 986–1001. Pubmed, doi:10.1152/jn.00209.2017. Full Text

Darlington, Timothy R., et al. “Control of the strength of visual-motor transmission as the mechanism of rapid adaptation of priors for Bayesian inference in smooth pursuit eye movements..” J Neurophysiol, vol. 118, no. 2, Aug. 2017, pp. 1173–89. Pubmed, doi:10.1152/jn.00282.2017. Full Text

Yang, Yan, and Stephen G. Lisberger. “Modulation of Complex-Spike Duration and Probability during Cerebellar Motor Learning in Visually Guided Smooth-Pursuit Eye Movements of Monkeys..” Eneuro, vol. 4, no. 3, May 2017. Pubmed, doi:10.1523/ENEURO.0115-17.2017. Full Text

Lee, Joonyeol, et al. “Signal, Noise, and Variation in Neural and Sensory-Motor Latency..” Neuron, vol. 90, no. 1, Apr. 2016, pp. 165–76. Pubmed, doi:10.1016/j.neuron.2016.02.012. Full Text

Lisberger, Stephen G. “Visual Guidance of Smooth Pursuit Eye Movements..” Annu Rev Vis Sci, vol. 1, Nov. 2015, pp. 447–68. Pubmed, doi:10.1146/annurev-vision-082114-035349. Full Text

Joshua, Mati, et al. “Interactions between target location and reward size modulate the rate of microsaccades in monkeys..” J Neurophysiol, vol. 114, no. 5, Nov. 2015, pp. 2616–24. Pubmed, doi:10.1152/jn.00401.2015. Full Text

Lisberger, Stephen G., and Javier F. Medina. “How and why neural and motor variation are related..” Curr Opin Neurobiol, vol. 33, Aug. 2015, pp. 110–16. Pubmed, doi:10.1016/j.conb.2015.03.008. Full Text

Joshua, M., and S. G. Lisberger. “A tale of two species: Neural integration in zebrafish and monkeys..” Neuroscience, vol. 296, June 2015, pp. 80–91. Pubmed, doi:10.1016/j.neuroscience.2014.04.048. Full Text

Pages

Boxer, A. L., et al. “The eyes have it: Distinct patterns of eye movement abnormalities in FTD relative to AD.” Neurology, vol. 64, no. 6, LIPPINCOTT WILLIAMS & WILKINS, 2005, pp. A100–A100.