Wolfgang Bernhard Liedtke

Wolfgang Bernhard Liedtke

Professor of Neurology

External Address: 
201G Bryan Res Bldg, Durham, NC 27710
Internal Office Address: 
Duke Box 2900, Durham, NC 27710


Research Interests in the Liedtke-Lab:

  • Pain/ nociception
  • Sensory transduction and -transmission
  • TRP ion channels
  • Water and salt equilibrium regulated by the central nervous system

Visit the lab's website, download papers and read Dr. Liedtke's CV here.

Education & Training

  • Resident, Psychiatry, University of Duisburg Essen (Germany) 1993 - 1994

  • Resident, Neurology, University of Duisburg Essen (Germany) 1991 - 1993

  • Resident, Neurology, University of Tubingen (Germany) 1989 - 1991

  • Ph.D., Ruhr-Universitat Bochum (Germany) 1990

  • Medicine/Surgery/Neurology Intenship, Surgery, Hôtel-Dieu de Paris (France) 1988 - 1989

  • M.D., University of Cologne, Faculty of Medicine (Germany) 1989

  • Medicine/Surgery/Neurology Intenship, Neurology, University Hospital Zurich (Switzerland) 1988 - 1988

Chen, Yong, et al. “Temporomandibular joint pain: a critical role for Trpv4 in the trigeminal ganglion.Pain, vol. 154, no. 8, Aug. 2013, pp. 1295–304. Pubmed, doi:10.1016/j.pain.2013.04.004. Full Text Open Access Copy

Fariss, M. W., et al. “Emerging mechanistic targets in lung injury induced by combustion-generated particles.” Toxicological Sciences, vol. 133, no. 1, May 2013, p. 196. Scopus, doi:10.1093/toxsci/kft074. Full Text

Dunn, Kathryn M., et al. “TRPV4 channels stimulate Ca2+-induced Ca2+ release in astrocytic endfeet and amplify neurovascular coupling responses.Proc Natl Acad Sci U S A, vol. 110, no. 15, Apr. 2013, pp. 6157–62. Pubmed, doi:10.1073/pnas.1216514110. Full Text

Fariss, Marc W., et al. “Emerging mechanistic targets in lung injury induced by combustion-generated particles.Toxicol Sci, vol. 132, no. 2, Apr. 2013, pp. 253–67. Pubmed, doi:10.1093/toxsci/kft001. Full Text

Yeo, Michele, et al. “Bisphenol A delays the perinatal chloride shift in cortical neurons by epigenetic effects on the Kcc2 promoter.Proc Natl Acad Sci U S A, vol. 110, no. 11, Mar. 2013, pp. 4315–20. Pubmed, doi:10.1073/pnas.1300959110. Full Text

Poole, Daniel P., et al. “Protease-activated receptor 2 (PAR2) protein and transient receptor potential vanilloid 4 (TRPV4) protein coupling is required for sustained inflammatory signaling.J Biol Chem, vol. 288, no. 8, Feb. 2013, pp. 5790–802. Pubmed, doi:10.1074/jbc.M112.438184. Full Text

O’Conor, Christopher J., et al. “Increased susceptibility of Trpv4-deficient mice to obesity and obesity-induced osteoarthritis with very high-fat diet.Ann Rheum Dis, vol. 72, no. 2, Feb. 2013, pp. 300–04. Pubmed, doi:10.1136/annrheumdis-2012-202272. Full Text

Ye, Li, et al. “TRPV4 is a regulator of adipose oxidative metabolism, inflammation, and energy homeostasis.Cell, vol. 151, no. 1, Sept. 2012, pp. 96–110. Pubmed, doi:10.1016/j.cell.2012.08.034. Full Text

Sonkusare, Swapnil K., et al. “Elementary Ca2+ signals through endothelial TRPV4 channels regulate vascular function.Science, vol. 336, no. 6081, May 2012, pp. 597–601. Pubmed, doi:10.1126/science.1216283. Full Text