Wolfgang Bernhard Liedtke

Wolfgang Bernhard Liedtke

Professor of Neurology

External Address: 
201G Bryan Res Bldg, Durham, NC 27710
Internal Office Address: 
Duke Box 2900, Durham, NC 27710


Research Interests in the Liedtke-Lab:

  • Pain/ nociception
  • Sensory transduction and -transmission
  • TRP ion channels
  • Water and salt equilibrium regulated by the central nervous system

Visit the lab's website, download papers and read Dr. Liedtke's CV here.

Education & Training

  • Resident, Psychiatry, University of Duisburg Essen (Germany) 1993 - 1994

  • Resident, Neurology, University of Duisburg Essen (Germany) 1991 - 1993

  • Resident, Neurology, University of Tubingen (Germany) 1989 - 1991

  • Ph.D., Ruhr-Universitat Bochum (Germany) 1990

  • Medicine/Surgery/Neurology Intenship, Surgery, Hôtel-Dieu de Paris (France) 1988 - 1989

  • M.D., University of Cologne, Faculty of Medicine (Germany) 1989

  • Medicine/Surgery/Neurology Intenship, Neurology, University Hospital Zurich (Switzerland) 1988 - 1988

Hamanaka, Kazutoshi, et al. “TRPV4 channels augment macrophage activation and ventilator-induced lung injury.Am J Physiol Lung Cell Mol Physiol, vol. 299, no. 3, Sept. 2010, pp. L353–62. Pubmed, doi:10.1152/ajplung.00315.2009. Full Text

Guilak, Farshid, et al. “Transient receptor potential vanilloid 4: The sixth sense of the musculoskeletal system?Ann N Y Acad Sci, vol. 1192, Mar. 2010, pp. 404–09. Pubmed, doi:10.1111/j.1749-6632.2010.05389.x. Full Text

Vergnolle, N., et al. “A role for transient receptor potential vanilloid 4 in tonicity-induced neurogenic inflammation.Br J Pharmacol, vol. 159, no. 5, Mar. 2010, pp. 1161–73. Pubmed, doi:10.1111/j.1476-5381.2009.00590.x. Full Text

Yeo, Michele, et al. “Novel repression of Kcc2 transcription by REST-RE-1 controls developmental switch in neuronal chloride.J Neurosci, vol. 29, no. 46, Nov. 2009, pp. 14652–62. Pubmed, doi:10.1523/JNEUROSCI.2934-09.2009. Full Text

Wu, Songwei, et al. “Ca2+ entry via alpha1G and TRPV4 channels differentially regulates surface expression of P-selectin and barrier integrity in pulmonary capillary endothelium.Am J Physiol Lung Cell Mol Physiol, vol. 297, no. 4, Oct. 2009, pp. L650–57. Pubmed, doi:10.1152/ajplung.00015.2009. Full Text

Phan, Mimi N., et al. “Functional characterization of TRPV4 as an osmotically sensitive ion channel in porcine articular chondrocytes.Arthritis Rheum, vol. 60, no. 10, Oct. 2009, pp. 3028–37. Pubmed, doi:10.1002/art.24799. Full Text

Earley, Scott, et al. “TRPV4-dependent dilation of peripheral resistance arteries influences arterial pressure.Am J Physiol Heart Circ Physiol, vol. 297, no. 3, Sept. 2009, pp. H1096–102. Pubmed, doi:10.1152/ajpheart.00241.2009. Full Text

Guilak, Farshid, et al. “Control of stem cell fate by physical interactions with the extracellular matrix.Cell Stem Cell, vol. 5, no. 1, July 2009, pp. 17–26. Pubmed, doi:10.1016/j.stem.2009.06.016. Full Text

Li, Jinju, et al. “Diesel exhaust particles activate the matrix-metalloproteinase-1 gene in human bronchial epithelia in a beta-arrestin-dependent manner via activation of RAS.Environ Health Perspect, vol. 117, no. 3, Mar. 2009, pp. 400–09. Pubmed, doi:10.1289/ehp.0800311. Full Text Open Access Copy

Liedtke, Wolfgang B. “AN UPDATE ON TRPV4-MEDIATED SIGNALING IN HEALTH AND DISEASE.” Journal of Physiological Sciences, vol. 59, SPRINGER TOKYO, Jan. 2009, pp. 93–93.